Genomic selection for improved crossbred performance

Marcos Soares Lopes

Research output: Thesisinternal PhD, WU

Abstract

Lopes, M.S. (2016). Genomic selection for improved crossbred performance. PhD thesis, Wageningen University, the Netherlands

With the implementation of genomic selection in pig breeding, the genetic progress in purebred populations is expected to increase up to 55% compared to traditional selection based on pedigree information. However, as most of the animals in the pork production system are crossbreds, the increase in genetic progress in purebreds will only be observed on production farms if this progress is expressed in the performance of crossbreds. The main aim of this thesis was to evaluate different models based on genomic information which can be applied to improve performance of crossbred animals. Another aim was to gain insight into genetic architecture of (complex) traits and to investigate how selection history has influenced haplotype patterns of current commercial pigs.  This thesis shows that by going beyond traditional genomic selection models, phenotypes can be predicted more accurately. Therefore, these improved models should be considered to improve crossbred performance. Further, this thesis provides important insights into the genetic architecture of the evaluated (complex) traits and also shows evidence that human-driven introgression and selection have shaped the genome of current commercial pig breeds. The research presented in this thesis was performed using data from pigs and the discussion on the practical application of results was focused on pig breeding. The results are relevant for all livestock species where crossbreeding is applied.

Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Wageningen University
Supervisors/Advisors
  • van Arendonk, Johan, Promotor
  • Bovenhuis, Henk, Co-promotor
  • Bastiaansen, John, Co-promotor
  • Knol, E.F., Co-promotor, External person
Award date19 Feb 2016
Place of PublicationWageningen
Publisher
Print ISBNs9789462576315
Publication statusPublished - 2016

Fingerprint

marker-assisted selection
crossbreds
livestock breeding
purebreds
swine
swine breeds
pedigree
introgression
pork
Netherlands
animals
haplotypes
production technology
livestock
genomics
phenotype
farms
history
genome

Keywords

  • pigs
  • crossbreds
  • genomics
  • selective breeding
  • performance
  • genetic improvement
  • pig breeding

Cite this

Lopes, M. S. (2016). Genomic selection for improved crossbred performance. Wageningen: Wageningen University.
Lopes, Marcos Soares. / Genomic selection for improved crossbred performance. Wageningen : Wageningen University, 2016. 202 p.
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Lopes, MS 2016, 'Genomic selection for improved crossbred performance', Doctor of Philosophy, Wageningen University, Wageningen.

Genomic selection for improved crossbred performance. / Lopes, Marcos Soares.

Wageningen : Wageningen University, 2016. 202 p.

Research output: Thesisinternal PhD, WU

TY - THES

T1 - Genomic selection for improved crossbred performance

AU - Lopes, Marcos Soares

N1 - WU thesis 6289

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N2 - Lopes, M.S. (2016). Genomic selection for improved crossbred performance. PhD thesis, Wageningen University, the Netherlands With the implementation of genomic selection in pig breeding, the genetic progress in purebred populations is expected to increase up to 55% compared to traditional selection based on pedigree information. However, as most of the animals in the pork production system are crossbreds, the increase in genetic progress in purebreds will only be observed on production farms if this progress is expressed in the performance of crossbreds. The main aim of this thesis was to evaluate different models based on genomic information which can be applied to improve performance of crossbred animals. Another aim was to gain insight into genetic architecture of (complex) traits and to investigate how selection history has influenced haplotype patterns of current commercial pigs.  This thesis shows that by going beyond traditional genomic selection models, phenotypes can be predicted more accurately. Therefore, these improved models should be considered to improve crossbred performance. Further, this thesis provides important insights into the genetic architecture of the evaluated (complex) traits and also shows evidence that human-driven introgression and selection have shaped the genome of current commercial pig breeds. The research presented in this thesis was performed using data from pigs and the discussion on the practical application of results was focused on pig breeding. The results are relevant for all livestock species where crossbreeding is applied.

AB - Lopes, M.S. (2016). Genomic selection for improved crossbred performance. PhD thesis, Wageningen University, the Netherlands With the implementation of genomic selection in pig breeding, the genetic progress in purebred populations is expected to increase up to 55% compared to traditional selection based on pedigree information. However, as most of the animals in the pork production system are crossbreds, the increase in genetic progress in purebreds will only be observed on production farms if this progress is expressed in the performance of crossbreds. The main aim of this thesis was to evaluate different models based on genomic information which can be applied to improve performance of crossbred animals. Another aim was to gain insight into genetic architecture of (complex) traits and to investigate how selection history has influenced haplotype patterns of current commercial pigs.  This thesis shows that by going beyond traditional genomic selection models, phenotypes can be predicted more accurately. Therefore, these improved models should be considered to improve crossbred performance. Further, this thesis provides important insights into the genetic architecture of the evaluated (complex) traits and also shows evidence that human-driven introgression and selection have shaped the genome of current commercial pig breeds. The research presented in this thesis was performed using data from pigs and the discussion on the practical application of results was focused on pig breeding. The results are relevant for all livestock species where crossbreeding is applied.

KW - pigs

KW - crossbreds

KW - genomics

KW - selective breeding

KW - performance

KW - genetic improvement

KW - pig breeding

KW - varkens

KW - kruising

KW - genomica

KW - selectief fokken

KW - prestatieniveau

KW - genetische verbetering

KW - varkensfokkerij

M3 - internal PhD, WU

SN - 9789462576315

PB - Wageningen University

CY - Wageningen

ER -

Lopes MS. Genomic selection for improved crossbred performance. Wageningen: Wageningen University, 2016. 202 p.