Like all plants, potato has evolved a surveillance system consisting of a large array of genes encoding for immune receptors that confer resistance to pathogens and pests. These so-called resistance or R proteins are composed of functional modules involved in pathogen recognition and the activation of a defence response. The majority of resistance genes identified to date belongs to the class of genes encoding nucleotide binding (NBS) and leucine rich repeats (LRR) domains. To date, more than twelve functional resistance genes are known in potato. In the potato genome sequence derived from the potato genotype DM1-3 516R44, 704 NB-LRR sequences have been identified. In another genotype i.e. RH89-039-16, 47 NB-LRR clusters have been sequenced and genetically mapped on the 12 potato chromosomes. Integration of the two datasets resulted in 45 different clusters that harboured at least one predicted full-length NB-LRR resistance gene and for which more than one homologous sequence has been identified. This dataset is currently used to study structural features and evolutionary dynamics of R genes in potato, but also to develop markers linked to disease resistance traits in potato.
|Publication status||Published - 16 Mar 2017|
|Event||5th Plant Genomics & Gene Editing Congress: Europe - Amsterdam, Netherlands|
Duration: 16 Mar 2017 → 17 Mar 2017
|Conference||5th Plant Genomics & Gene Editing Congress: Europe|
|Period||16/03/17 → 17/03/17|