Genome-wide association study of the de novo synthesized milk fatty acids based on Dutch, Danish and Chinese Holstein Friesians

Grum Gebreyesus; Bart Buitenhuis; Nina A. Poulsen; M.H.P.W. Visker; Qianqian Zhang; H.J.F. van Valenberg; D. Sun; H. Bovenhuis

Genome-wide association study of the de novo synthesized milk fatty acids based on Dutch, Danish and Chinese Holstein Friesians

Grum Gebreyesus, Bart Buitenhuis, Nina A. Poulsen, M.H.P.W. Visker, Qianqian Zhang, H.J.F. van Valenberg, D. Sun, H. Bovenhuis

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › Academic

Abstract

Data for the de novo synthesized milk fatty acids (FAs) were obtained from milk samples of 1736 Dutch, 675 Danish and 784 Chinese Holstein Friesian cows and combined for multipopulation genome-wide association study (GWAS) using a mixed linear model. Results were compared with population specific GWAS undertaken for each population. In the combined analysis, QTL regions spread across 16 chromosomes were found significantly associated with the de novo synthesized FAs. Compared to the population-specific analyses, our multipopulation GWAS resulted in more regions showing significant associations for the de novo synthesized FAs, some of which were not previously reported.

Original language	English
Title of host publication	Proceedings of the World Congress on Genetics Applied to Livestock Production
Subtitle of host publication	Volume Biology & Species - Bovine (dairy) 2
Publisher	WCGALP
Number of pages	6
Publication status	Published - Feb 2018
Event	11th World Congress on Genetics Applied to Livestock Production - Auckland, New Zealand Duration: 11 Feb 2018 → 16 Feb 2018

Conference/symposium

Conference/symposium	11th World Congress on Genetics Applied to Livestock Production
Country/Territory	New Zealand
City	Auckland
Period	11/02/18 → 16/02/18

Access to Document

http://www.wcgalp.org/proceedings/2018/genome-wide-association-study-de-novo-synthesized-milk-fatty-acids-based-dutchLicence: CC BY-NC-ND

Cite this

Gebreyesus, G., Buitenhuis, B., Poulsen, N. A., Visker, M. H. P. W., Zhang, Q., van Valenberg, H. J. F., Sun, D., & Bovenhuis, H. (2018). Genome-wide association study of the de novo synthesized milk fatty acids based on Dutch, Danish and Chinese Holstein Friesians. In Proceedings of the World Congress on Genetics Applied to Livestock Production: Volume Biology & Species - Bovine (dairy) 2 Article 141 WCGALP. http://www.wcgalp.org/proceedings/2018/genome-wide-association-study-de-novo-synthesized-milk-fatty-acids-based-dutch

@inproceedings{4ca6732a4d494a2e97ea0bd5d153e49b,

title = "Genome-wide association study of the de novo synthesized milk fatty acids based on Dutch, Danish and Chinese Holstein Friesians",

abstract = "Data for the de novo synthesized milk fatty acids (FAs) were obtained from milk samples of 1736 Dutch, 675 Danish and 784 Chinese Holstein Friesian cows and combined for multipopulation genome-wide association study (GWAS) using a mixed linear model. Results were compared with population specific GWAS undertaken for each population. In the combined analysis, QTL regions spread across 16 chromosomes were found significantly associated with the de novo synthesized FAs. Compared to the population-specific analyses, our multipopulation GWAS resulted in more regions showing significant associations for the de novo synthesized FAs, some of which were not previously reported.",

author = "Grum Gebreyesus and Bart Buitenhuis and Poulsen, \{Nina A.\} and M.H.P.W. Visker and Qianqian Zhang and \{van Valenberg\}, H.J.F. and D. Sun and H. Bovenhuis",

year = "2018",

month = feb,

language = "English",

booktitle = "Proceedings of the World Congress on Genetics Applied to Livestock Production",

publisher = "WCGALP",

note = "11th World Congress on Genetics Applied to Livestock Production ; Conference date: 11-02-2018 Through 16-02-2018",

}

Gebreyesus, G, Buitenhuis, B, Poulsen, NA, Visker, MHPW, Zhang, Q, van Valenberg, HJF, Sun, D & Bovenhuis, H 2018, Genome-wide association study of the de novo synthesized milk fatty acids based on Dutch, Danish and Chinese Holstein Friesians. in Proceedings of the World Congress on Genetics Applied to Livestock Production: Volume Biology & Species - Bovine (dairy) 2., 141, WCGALP, 11th World Congress on Genetics Applied to Livestock Production, Auckland, New Zealand, 11/02/18. <http://www.wcgalp.org/proceedings/2018/genome-wide-association-study-de-novo-synthesized-milk-fatty-acids-based-dutch>

Genome-wide association study of the de novo synthesized milk fatty acids based on Dutch, Danish and Chinese Holstein Friesians. / Gebreyesus, Grum; Buitenhuis, Bart; Poulsen, Nina A. et al.
Proceedings of the World Congress on Genetics Applied to Livestock Production: Volume Biology & Species - Bovine (dairy) 2. WCGALP, 2018. 141.

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › Academic

TY - GEN

T1 - Genome-wide association study of the de novo synthesized milk fatty acids based on Dutch, Danish and Chinese Holstein Friesians

AU - Gebreyesus, Grum

AU - Buitenhuis, Bart

AU - Poulsen, Nina A.

AU - Visker, M.H.P.W.

AU - Zhang, Qianqian

AU - van Valenberg, H.J.F.

AU - Sun, D.

AU - Bovenhuis, H.

PY - 2018/2

Y1 - 2018/2

N2 - Data for the de novo synthesized milk fatty acids (FAs) were obtained from milk samples of 1736 Dutch, 675 Danish and 784 Chinese Holstein Friesian cows and combined for multipopulation genome-wide association study (GWAS) using a mixed linear model. Results were compared with population specific GWAS undertaken for each population. In the combined analysis, QTL regions spread across 16 chromosomes were found significantly associated with the de novo synthesized FAs. Compared to the population-specific analyses, our multipopulation GWAS resulted in more regions showing significant associations for the de novo synthesized FAs, some of which were not previously reported.

AB - Data for the de novo synthesized milk fatty acids (FAs) were obtained from milk samples of 1736 Dutch, 675 Danish and 784 Chinese Holstein Friesian cows and combined for multipopulation genome-wide association study (GWAS) using a mixed linear model. Results were compared with population specific GWAS undertaken for each population. In the combined analysis, QTL regions spread across 16 chromosomes were found significantly associated with the de novo synthesized FAs. Compared to the population-specific analyses, our multipopulation GWAS resulted in more regions showing significant associations for the de novo synthesized FAs, some of which were not previously reported.

M3 - Conference paper

BT - Proceedings of the World Congress on Genetics Applied to Livestock Production

PB - WCGALP

T2 - 11th World Congress on Genetics Applied to Livestock Production

Y2 - 11 February 2018 through 16 February 2018

ER -

Genome-wide association study of the de novo synthesized milk fatty acids based on Dutch, Danish and Chinese Holstein Friesians

Abstract

Conference/symposium

Access to Document

Fingerprint

Cite this