Equine osteochondrosis is a developmental joint disease that is a significant source of morbidity affecting multiple breeds of horse. The genetic variants underlying osteochondrosis susceptibility have not been established. Here, we describe the results of a genome-wide association study of osteochondrosis using 90 cases and 111 controls from a population of Dutch Warmblood horses. We report putative associations between osteochondrosis and loci on chromosome 3 (BIEC2-808543; P = 5.03 × 10-7) and chromosome 10 (BIEC2-121323; P = 2.62 × 10-7).
- german coldblood horses
Orr, N., Hill, E. W., Gu, G., Govindarajan, P., Conroy, J., van Grevenhof, E. M., ... Brama, P. A. (2013). Genome-wide association study of osteochondrosis in the tarsocrural joint of Dutch Warmblood horses identifies susceptibility loci on chromosomes 3 and 10. Animal Genetics, 44(4), 408-412. https://doi.org/10.1111/age.12016