Genome analysis of the necrotrophic fungal pathogens Sclerotinia sclerotiorum and Botrytis cinerea

J. Amselem, C.A. Cuomo, J.A.L. van Kan, M. Viaud, E.P. Benito, A. Couloux, P.M. Coutinho, R.P. de Vries, P.S. Dyer, S. Fillinger, E. Fournier, L. Gout, M. Hahn, L. Kohn, N. Lapalu, K.M. Plummer, J.M. Pradier, E. Quévillon, A. Sharon, A. SimonA. ten Have, B. Tudzynski, P. Tudzynski, P. Wincker, M. Andrew, V. Anthouard, R.E. Beever, R. Beffa, I. Benoit, O. Bouzid, B. Brault, Z. Chen, M. Choquer, J. Collemare, P. Cotton, E.G. Danchin, C. Da Silva, A. Gautier, C. Giraud, T. Giraud, C. Gonzalez, S. Grossetete, U. Güldener, B. Henrissat, B.J. Howlett, C. Kodira, M. Kretschmer, A. Lappartient, M. Leroch, C. Levis, E. Mauceli, C. Neuvéglise, B. Oeser, M. Pearson, J. Poulain, N. Poussereau, H. Quesneville, C. Rascle, J. Schumacher, B. Ségurens, A. Sexton, E. Silva, C. Sirven, D.M. Soanes, N.J. Talbot, M. Templeton, C. Yandava, O. Yarden, Q. Zeng, J.A. Rollins, M.H. Lebrun, M. Dickman

Research output: Contribution to journalArticleAcademicpeer-review

588 Citations (Scopus)

Abstract

Sclerotinia sclerotiorum and Botrytis cinerea are closely related necrotrophic plant pathogenic fungi notable for their wide host ranges and environmental persistence. These attributes have made these species models for understanding the complexity of necrotrophic, broad host-range pathogenicity. Despite their similarities, the two species differ in mating behaviour and the ability to produce asexual spores. We have sequenced the genomes of one strain of S. sclerotiorum and two strains of B. cinerea. The comparative analysis of these genomes relative to one another and to other sequenced fungal genomes is provided here. Their 38–39 Mb genomes include 11,860–14,270 predicted genes, which share 83% amino acid identity on average between the two species. We have mapped the S. sclerotiorum assembly to 16 chromosomes and found large-scale co-linearity with the B. cinerea genomes. Seven percent of the S. sclerotiorum genome comprises transposable elements compared to
Original languageEnglish
Article numbere1002230
Number of pages27
JournalPlos Genetics
Volume7
Issue number8
DOIs
Publication statusPublished - 2011

Keywords

  • rice blast fungus
  • development-specific protein
  • expressed sequence tags
  • programmed cell-death
  • mating-type loci
  • oxalic-acid
  • neurospora-crassa
  • arabidopsis-thaliana
  • secondary metabolism
  • molecular phylogeny

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