In the United States and globally, producers cultivate millions of hectares of genetically modified crops. In the United States, the USDA, EPA, and FDA govern authorization of GMOs under federal laws and agency regulations. Because food produced from GMOs is not considered materially different from conventional food, federal laws require no special labels. To address consumer concerns, states are considering label requirements. Tort remedies are available to redress damage from GMOs, but litigation has not focused on harm from GM food. GM technology is controversial, and many nations have imposed regulatory barriers or prohibitions. In the coming decades, however, GM crops may help to satisfy global demand for food and to meet the challenges of climate change.