Genetic Safeguards for Safety-by-design: So Close Yet So Far

E. Asín García, Amalia Kallergi, Laurens Landeweerd, V.A.P. Martins dos Santos

Research output: Contribution to journalArticleAcademicpeer-review


Safety-by-design (SbD) is paramount for risk management in synthetic biology, with genetic safeguards being a key technology for its implementation. While attractive in theory, the integration of genetic safeguards into SbD strategies is rarely exercised in practice, despite technological advances. Here we question why and what might be done about it.
Original languageEnglish
Article number1016
JournalTrends in Biotechnology
Publication statusE-pub ahead of print - 10 May 2020

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