Generation of LTB-based mucosal vaccines and production in plants

D.E.A. Florack; C.I. Matos; G.J.A. Rouwendal; H.J. Bosch

Generation of LTB-based mucosal vaccines and production in plants

D.E.A. Florack, C.I. Matos, G.J.A. Rouwendal, H.J. Bosch

Research output: Contribution to journal › Abstract › Academic

Abstract

A number of recombinant B subunit-fusion proteins comprising either small and linear B and/or T cell epitope sequences, a large structural N-glycosylated viral surface antigen and two reporter enzymatic entities were expressed in potato tubers. All could be functionally expressed as determined by a GM1-ELISA but actual levels varied significantly and decreased strongly upon increased complexity

Original language	English
Pages (from-to)	399-400
Journal	Journal of Controlled Release
Volume	101
Issue number	1-3
Publication status	Published - 2005

Keywords

transgenic plants
oral immunization
cholera-toxin
subunit

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

@article{67589ed24c9144ffa7c857930ff05e4c,

title = "Generation of LTB-based mucosal vaccines and production in plants",

abstract = "A number of recombinant B subunit-fusion proteins comprising either small and linear B and/or T cell epitope sequences, a large structural N-glycosylated viral surface antigen and two reporter enzymatic entities were expressed in potato tubers. All could be functionally expressed as determined by a GM1-ELISA but actual levels varied significantly and decreased strongly upon increased complexity",

keywords = "transgenic plants, oral immunization, cholera-toxin, subunit",

author = "D.E.A. Florack and C.I. Matos and G.J.A. Rouwendal and H.J. Bosch",

year = "2005",

language = "English",

volume = "101",

pages = "399--400",

journal = "Journal of Controlled Release",

issn = "0168-3659",

publisher = "Elsevier",

number = "1-3",

}

TY - JOUR

T1 - Generation of LTB-based mucosal vaccines and production in plants

AU - Florack, D.E.A.

AU - Matos, C.I.

AU - Rouwendal, G.J.A.

AU - Bosch, H.J.

PY - 2005

Y1 - 2005

N2 - A number of recombinant B subunit-fusion proteins comprising either small and linear B and/or T cell epitope sequences, a large structural N-glycosylated viral surface antigen and two reporter enzymatic entities were expressed in potato tubers. All could be functionally expressed as determined by a GM1-ELISA but actual levels varied significantly and decreased strongly upon increased complexity

AB - A number of recombinant B subunit-fusion proteins comprising either small and linear B and/or T cell epitope sequences, a large structural N-glycosylated viral surface antigen and two reporter enzymatic entities were expressed in potato tubers. All could be functionally expressed as determined by a GM1-ELISA but actual levels varied significantly and decreased strongly upon increased complexity

KW - transgenic plants

KW - oral immunization

KW - cholera-toxin

KW - subunit

M3 - Abstract

SN - 0168-3659

VL - 101

SP - 399

EP - 400

JO - Journal of Controlled Release

JF - Journal of Controlled Release

IS - 1-3

ER -

Generation of LTB-based mucosal vaccines and production in plants

Abstract

Keywords

UN SDGs

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Cite this