Gene for gene models and beyond: the Cladosporium fulvum-tomato pathosystem

P.J.G.M. de Wit, M.H.A.J. Joosten, B.P.H.J. Thomma, I. Stergiopoulos

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review


The fungal pathogen Cladosporium fulvum causes leaf mould of tomato, a disease that causes serious economic losses to tomatoes that lack C. fulvum (Cf) resistance genes. The availability of near-isogenic lines of tomato carrying different Cf genes and a large collection of C. fulvum races carrying different avirulence (Avr) genes has made this pathosystem an ideal model to study the molecular basis of gene-for-gene interactions. Cf proteins mediate a defense response in the presence of a cognate Avr protein. In the absence of a cognate Cf protein, an Avr protein functions as a virulence factor, facilitating infection of the host plant. Both functions of Avr proteins will be discussed as well as the cascade of defense responses induced by them and mediated by cognate Cf proteins
Original languageEnglish
Title of host publicationPlant Relationships
EditorsH.B. Deising
Place of PublicationBerlin Heidelberg
Publication statusPublished - 2009

Publication series

NameThe Mycota
NumberVol. 5


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