Functional diversification of a wild potato immune receptor at its center of origin

Yerisf C. Torres Ascurra, Lisha Zhang, Amir Ali Toghani, Chenlei Hua, Nandeesh Jalahalli Rangegowda, Andres Posbeyikian, Hsuan Pai, Xiao Lin, Pieter J. Wolters, Doret Wouters, Reinhoud de Blok, Niels Steigenga, Maxence J.M. Paillart, Richard G.F. Visser, Sophien Kamoun, Thorsten Nürnberger*, Vivianne G.A.A. Vleeshouwers*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Abstract

Plant cell surface pattern recognition receptors (PRRs) and intracellular immune receptors cooperate to provide immunity to microbial infection. Both receptor families have coevolved at an accelerated rate, but the evolution and diversification of PRRs is poorly understood. We have isolated potato surface receptor Pep-13 receptor unit (PERU) that senses Pep-13, a conserved immunogenic peptide pattern from plant pathogenic Phytophthora species. PERU, a leucine-rich repeat receptor kinase, is a bona fide PRR that binds Pep-13 and enhances immunity to Phytophthora infestans infection. Diversification in ligand binding specificities of PERU can be traced to sympatric wild tuber-bearing Solanum populations in the Central Andes. Our study reveals the evolution of cell surface immune receptor alleles in wild potato populations that recognize ligand variants not recognized by others.

Original languageEnglish
Pages (from-to)891-897
Number of pages7
JournalScience (New York, N.Y.)
Volume381
Issue number6660
DOIs
Publication statusPublished - 25 Aug 2023

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