Function of the opioid system during inflammation in carp

B.M.L. Verburg-van Kemenade, H.F.J. Savelkoul, M.K. Chadzinska

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Citations (Scopus)

Abstract

The opioid system is involved in modulation of both innate and acquired immune responses, thus altering resistance to a variety of infectious agents. We sequenced and characterized carp opioid receptors (MOR, DOR, and KOR) and found their regulated expression in piscine leukocytes. Moreover, both in vivo and in vitro opioids affect activity of leukocytes and expression of inflammatory molecules, especially chemokines and chemokine receptors. Our data indicate an evolutionary conserved role for the opioid system in immune regulation
Original languageEnglish
Title of host publicationTrends in Comparative Endocrinology and Neurobiology
EditorsH. Vaudry, E.W. Roubos, G. Coast, M. Vallarino
Place of Publication[S.l.]
PublisherWiley-Blackwell
Pages528-532
ISBN (Print)9781573316712
DOIs
Publication statusPublished - 2009

Fingerprint

Carps
Opioid Analgesics
Inflammation
Leukocytes
Chemokine Receptors
Opioid Receptors
Chemokines
Innate Immunity
Immune System

Keywords

  • beta-endorphin
  • in-vitro
  • fish
  • receptors
  • modulation
  • leukocytes
  • innate

Cite this

Verburg-van Kemenade, B. M. L., Savelkoul, H. F. J., & Chadzinska, M. K. (2009). Function of the opioid system during inflammation in carp. In H. Vaudry, E. W. Roubos, G. Coast, & M. Vallarino (Eds.), Trends in Comparative Endocrinology and Neurobiology (pp. 528-532). [S.l.]: Wiley-Blackwell. https://doi.org/10.1111/j.1749-6632.2008.03673.x
Verburg-van Kemenade, B.M.L. ; Savelkoul, H.F.J. ; Chadzinska, M.K. / Function of the opioid system during inflammation in carp. Trends in Comparative Endocrinology and Neurobiology. editor / H. Vaudry ; E.W. Roubos ; G. Coast ; M. Vallarino. [S.l.] : Wiley-Blackwell, 2009. pp. 528-532
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Verburg-van Kemenade, BML, Savelkoul, HFJ & Chadzinska, MK 2009, Function of the opioid system during inflammation in carp. in H Vaudry, EW Roubos, G Coast & M Vallarino (eds), Trends in Comparative Endocrinology and Neurobiology. Wiley-Blackwell, [S.l.], pp. 528-532. https://doi.org/10.1111/j.1749-6632.2008.03673.x

Function of the opioid system during inflammation in carp. / Verburg-van Kemenade, B.M.L.; Savelkoul, H.F.J.; Chadzinska, M.K.

Trends in Comparative Endocrinology and Neurobiology. ed. / H. Vaudry; E.W. Roubos; G. Coast; M. Vallarino. [S.l.] : Wiley-Blackwell, 2009. p. 528-532.

Research output: Chapter in Book/Report/Conference proceedingChapter

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KW - receptors

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BT - Trends in Comparative Endocrinology and Neurobiology

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Verburg-van Kemenade BML, Savelkoul HFJ, Chadzinska MK. Function of the opioid system during inflammation in carp. In Vaudry H, Roubos EW, Coast G, Vallarino M, editors, Trends in Comparative Endocrinology and Neurobiology. [S.l.]: Wiley-Blackwell. 2009. p. 528-532 https://doi.org/10.1111/j.1749-6632.2008.03673.x