Four independent molecular prion protein parameters for discriminating new cases of C, L, and H BSE in cattle.

J.P.M. Langeveld; J.H.F. Erkens; I. Rammel; J.G. Jacobs; A. Davidse; F.G. van Zijderveld; A. Bossers; H. Schildorfer

doi:10.1128/JCM.01102-11

Four independent molecular prion protein parameters for discriminating new cases of C, L, and H BSE in cattle.

J.P.M. Langeveld
, J.H.F. Erkens
, I. Rammel
, J.G. Jacobs
, A. Davidse
, F.G. van Zijderveld
, A. Bossers
, H. Schildorfer

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

Abstract

In anticipation of the emergence of more variants of bovine spongiform encephalopathy (BSE), a semiquantitative display of the following four independent molecular diagnostic prion parameters was designed: N terminus, proteinase K (PK) resistance, glycoprofile, and mixed population. One H BSE case, three L BSE cases, six C BSE cases, and one unusual classical BSE (C BSE) case are reported.

Original language	English
Pages (from-to)	3026-3028
Journal	Journal of Clinical Microbiology
Volume	49
Issue number	8
DOIs	https://doi.org/10.1128/JCM.01102-11
Publication status	Published - 2011

Keywords

monoclonal-antibodies
great-britain
atypical bse
identification
similarities
diseases
prpsc
rich

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10.1128/JCM.01102-11

TSE's (WOT-01-002-031, WOT-01-002-001.01)
van Keulen, L. (Project Leader)
1/01/08 → 31/12/26
Project: LVVN project

Cite this

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title = "Four independent molecular prion protein parameters for discriminating new cases of C, L, and H BSE in cattle.",

abstract = "In anticipation of the emergence of more variants of bovine spongiform encephalopathy (BSE), a semiquantitative display of the following four independent molecular diagnostic prion parameters was designed: N terminus, proteinase K (PK) resistance, glycoprofile, and mixed population. One H BSE case, three L BSE cases, six C BSE cases, and one unusual classical BSE (C BSE) case are reported.",

keywords = "monoclonal-antibodies, great-britain, atypical bse, identification, similarities, diseases, prpsc, rich",

author = "J.P.M. Langeveld and J.H.F. Erkens and I. Rammel and J.G. Jacobs and A. Davidse and \{van Zijderveld\}, F.G. and A. Bossers and H. Schildorfer",

year = "2011",

doi = "10.1128/JCM.01102-11",

language = "English",

volume = "49",

pages = "3026--3028",

journal = "Journal of Clinical Microbiology",

issn = "0095-1137",

publisher = "American Society for Microbiology",

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TY - JOUR

T1 - Four independent molecular prion protein parameters for discriminating new cases of C, L, and H BSE in cattle.

AU - Langeveld, J.P.M.

AU - Erkens, J.H.F.

AU - Rammel, I.

AU - Jacobs, J.G.

AU - Davidse, A.

AU - van Zijderveld, F.G.

AU - Bossers, A.

AU - Schildorfer, H.

PY - 2011

Y1 - 2011

N2 - In anticipation of the emergence of more variants of bovine spongiform encephalopathy (BSE), a semiquantitative display of the following four independent molecular diagnostic prion parameters was designed: N terminus, proteinase K (PK) resistance, glycoprofile, and mixed population. One H BSE case, three L BSE cases, six C BSE cases, and one unusual classical BSE (C BSE) case are reported.

AB - In anticipation of the emergence of more variants of bovine spongiform encephalopathy (BSE), a semiquantitative display of the following four independent molecular diagnostic prion parameters was designed: N terminus, proteinase K (PK) resistance, glycoprofile, and mixed population. One H BSE case, three L BSE cases, six C BSE cases, and one unusual classical BSE (C BSE) case are reported.

KW - monoclonal-antibodies

KW - great-britain

KW - atypical bse

KW - identification

KW - similarities

KW - diseases

KW - prpsc

KW - rich

U2 - 10.1128/JCM.01102-11

DO - 10.1128/JCM.01102-11

M3 - Article

SN - 0095-1137

VL - 49

SP - 3026

EP - 3028

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

IS - 8

ER -

Four independent molecular prion protein parameters for discriminating new cases of C, L, and H BSE in cattle.

Abstract

Keywords

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Projects

TSE's (WOT-01-002-031, WOT-01-002-001.01)

Cite this