Four independent molecular prion protein parameters for discriminating new cases of C, L, and H BSE in cattle.

J.P.M. Langeveld, J.H.F. Erkens, I. Rammel, J.G. Jacobs, A. Davidse, F.G. van Zijderveld, A. Bossers, H. Schildorfer

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11 Citations (Scopus)

Abstract

In anticipation of the emergence of more variants of bovine spongiform encephalopathy (BSE), a semiquantitative display of the following four independent molecular diagnostic prion parameters was designed: N terminus, proteinase K (PK) resistance, glycoprofile, and mixed population. One H BSE case, three L BSE cases, six C BSE cases, and one unusual classical BSE (C BSE) case are reported.
Original languageEnglish
Pages (from-to)3026-3028
JournalJournal of Clinical Microbiology
Volume49
Issue number8
DOIs
Publication statusPublished - 2011

Keywords

  • monoclonal-antibodies
  • great-britain
  • atypical bse
  • identification
  • similarities
  • diseases
  • prpsc
  • rich

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    van Keulen, L.

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    Cite this

    Langeveld, J. P. M., Erkens, J. H. F., Rammel, I., Jacobs, J. G., Davidse, A., van Zijderveld, F. G., Bossers, A., & Schildorfer, H. (2011). Four independent molecular prion protein parameters for discriminating new cases of C, L, and H BSE in cattle. Journal of Clinical Microbiology, 49(8), 3026-3028. https://doi.org/10.1128/JCM.01102-11