Firing Up Glycolysis: BCG Vaccination Effects on Type 1 Diabetes Mellitus

Rinke Stienstra; Mihai G. Netea

doi:10.1016/j.tem.2018.10.001

Firing Up Glycolysis: BCG Vaccination Effects on Type 1 Diabetes Mellitus

Rinke Stienstra, Mihai G. Netea^*

^*Corresponding author for this work

Nutrition, Metabolism and Genomics

Research output: Contribution to journal › Article › Academic › peer-review

7 Citations (Scopus)

Abstract

In addition to the impact of Bacillus Calmette–Guerin (BCG) vaccination on antimicrobial host defence, a novel study reveals beneficial effects on glycaemic control in patients with long-standing type 1 diabetes mellitus (T1DM). These effects are ascribed to an accelerated glucose consumption in immune cells due to increased glycolysis and reduced oxidative phosphorylation.

Original language	English
Pages (from-to)	813-814
Journal	Trends in Endocrinology and Metabolism
Volume	29
Issue number	12
Early online date	13 Oct 2018
DOIs	https://doi.org/10.1016/j.tem.2018.10.001
Publication status	Published - Dec 2018

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10.1016/j.tem.2018.10.001

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title = "Firing Up Glycolysis: BCG Vaccination Effects on Type 1 Diabetes Mellitus",

abstract = "In addition to the impact of Bacillus Calmette–Guerin (BCG) vaccination on antimicrobial host defence, a novel study reveals beneficial effects on glycaemic control in patients with long-standing type 1 diabetes mellitus (T1DM). These effects are ascribed to an accelerated glucose consumption in immune cells due to increased glycolysis and reduced oxidative phosphorylation.",

author = "Rinke Stienstra and Netea, {Mihai G.}",

year = "2018",

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T2 - BCG Vaccination Effects on Type 1 Diabetes Mellitus

AU - Stienstra, Rinke

AU - Netea, Mihai G.

PY - 2018/12

Y1 - 2018/12

N2 - In addition to the impact of Bacillus Calmette–Guerin (BCG) vaccination on antimicrobial host defence, a novel study reveals beneficial effects on glycaemic control in patients with long-standing type 1 diabetes mellitus (T1DM). These effects are ascribed to an accelerated glucose consumption in immune cells due to increased glycolysis and reduced oxidative phosphorylation.

AB - In addition to the impact of Bacillus Calmette–Guerin (BCG) vaccination on antimicrobial host defence, a novel study reveals beneficial effects on glycaemic control in patients with long-standing type 1 diabetes mellitus (T1DM). These effects are ascribed to an accelerated glucose consumption in immune cells due to increased glycolysis and reduced oxidative phosphorylation.

U2 - 10.1016/j.tem.2018.10.001

DO - 10.1016/j.tem.2018.10.001

M3 - Article

AN - SCOPUS:85054641317

VL - 29

SP - 813

EP - 814

JO - Trends in Endocrinology & Metabolism

JF - Trends in Endocrinology & Metabolism

SN - 1043-2760

IS - 12

ER -

Firing Up Glycolysis: BCG Vaccination Effects on Type 1 Diabetes Mellitus

Abstract

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