Feasibility study Open MCRA

Johannes W. Kruisselbrink; Marco S. van Lenthe; Hilko van der Voet; Waldo J. de Boer; Jacob D. van Klaveren

doi:10.2903/sp.efsa.2021.EN-6515

Feasibility study Open MCRA

Johannes W. Kruisselbrink^*, Marco S. van Lenthe, Hilko van der Voet, Waldo J. de Boer, Jacob D. van Klaveren

^*Corresponding author for this work

Biometris

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

This report presents the results of a feasibility study for improving transparency and accessibility of the models implemented in the Monte Carlo Risk Assessment (MCRA) web platform for assessing the risk of combined exposure to multiple chemicals via multiple exposure routes. It provides an overview of the history and current use of the web platform and its scientific and regulatory context. The technical infrastructure of the current MCRA web platform and the modular design of the various models of MCRA are described. Based on selected user stories, user requirements are established, and suggestions are made for possible designs of an open source collection of MCRA models. Technical options are listed for code organisation, programming language, interfacing and containerisation, data organisation, storage and licensing.Also, the role of the MCRA web platform is discussed. The report ends with a suggested approach and next steps, includinga discussion on the need for a governance structure for sustainable development of Open MCRA.

Original language	English
Journal	EFSA Supporting Publications
Volume	18
Issue number	4
DOIs	https://doi.org/10.2903/sp.efsa.2021.EN-6515
Publication status	Published - 1 Apr 2021

Access to Document

10.2903/sp.efsa.2021.EN-6515Licence: Open Access other

1 Software

MCRA Core
Kruisselbrink, J. W., Engel, J., van Voorthuijsen, T., de Boer, W. J., van Lenthe, M. S., van der Voet, H., van Donkersgoed, G., Chen, G., De Jong, E. & van Klaveren, J., 21 Dec 2023
Research output: Non-textual form › Software

Open Access

Cite this

@article{05efdde084624cf59d9674684c36ed6a,

title = "Feasibility study Open MCRA",

abstract = "This report presents the results of a feasibility study for improving transparency and accessibility of the models implemented in the Monte Carlo Risk Assessment (MCRA) web platform for assessing the risk of combined exposure to multiple chemicals via multiple exposure routes. It provides an overview of the history and current use of the web platform and its scientific and regulatory context. The technical infrastructure of the current MCRA web platform and the modular design of the various models of MCRA are described. Based on selected user stories, user requirements are established, and suggestions are made for possible designs of an open source collection of MCRA models. Technical options are listed for code organisation, programming language, interfacing and containerisation, data organisation, storage and licensing.Also, the role of the MCRA web platform is discussed. The report ends with a suggested approach and next steps, includinga discussion on the need for a governance structure for sustainable development of Open MCRA.",

author = "Kruisselbrink, {Johannes W.} and {van Lenthe}, {Marco S.} and {van der Voet}, Hilko and {de Boer}, {Waldo J.} and {van Klaveren}, {Jacob D.}",

year = "2021",

month = apr,

day = "1",

doi = "10.2903/sp.efsa.2021.EN-6515",

language = "English",

volume = "18",

journal = "EFSA Supporting Publications",

issn = "2397-8325",

publisher = "EFSA",

number = "4",

}

TY - JOUR

T1 - Feasibility study Open MCRA

AU - Kruisselbrink, Johannes W.

AU - van Lenthe, Marco S.

AU - van der Voet, Hilko

AU - de Boer, Waldo J.

AU - van Klaveren, Jacob D.

PY - 2021/4/1

Y1 - 2021/4/1

N2 - This report presents the results of a feasibility study for improving transparency and accessibility of the models implemented in the Monte Carlo Risk Assessment (MCRA) web platform for assessing the risk of combined exposure to multiple chemicals via multiple exposure routes. It provides an overview of the history and current use of the web platform and its scientific and regulatory context. The technical infrastructure of the current MCRA web platform and the modular design of the various models of MCRA are described. Based on selected user stories, user requirements are established, and suggestions are made for possible designs of an open source collection of MCRA models. Technical options are listed for code organisation, programming language, interfacing and containerisation, data organisation, storage and licensing.Also, the role of the MCRA web platform is discussed. The report ends with a suggested approach and next steps, includinga discussion on the need for a governance structure for sustainable development of Open MCRA.

AB - This report presents the results of a feasibility study for improving transparency and accessibility of the models implemented in the Monte Carlo Risk Assessment (MCRA) web platform for assessing the risk of combined exposure to multiple chemicals via multiple exposure routes. It provides an overview of the history and current use of the web platform and its scientific and regulatory context. The technical infrastructure of the current MCRA web platform and the modular design of the various models of MCRA are described. Based on selected user stories, user requirements are established, and suggestions are made for possible designs of an open source collection of MCRA models. Technical options are listed for code organisation, programming language, interfacing and containerisation, data organisation, storage and licensing.Also, the role of the MCRA web platform is discussed. The report ends with a suggested approach and next steps, includinga discussion on the need for a governance structure for sustainable development of Open MCRA.

U2 - 10.2903/sp.efsa.2021.EN-6515

DO - 10.2903/sp.efsa.2021.EN-6515

M3 - Article

SN - 2397-8325

VL - 18

JO - EFSA Supporting Publications

JF - EFSA Supporting Publications

IS - 4

ER -

Feasibility study Open MCRA

Abstract

Access to Document

Fingerprint

Research output

MCRA Core

Cite this