Fat, fibre and cancer risk in African Americans and rural Africans

S.J. O'Keefe, J.V. Li, L.M. Lahti, J. Ou, F. Carbonero, K. Mohammed, J.M. Posma, J. Kinross, E. Wahl, E. Ruder, K. Vipperla, V. Naidoo, L. Mtshali, S. Tims, P.G.B. Puylaert, J. DeLany, A. Krasinskas, A.C. Benefiel, H.O. Kaseb, K. NewtonJ.K. Nicholson, W.M. de Vos, H.R. Gaskins, E.G. Zoetendal

Research output: Contribution to journalArticleAcademicpeer-review

360 Citations (Scopus)

Abstract

Rates of colon cancer are much higher in African Americans (65:100,000) than in rural South Africans (
Original languageEnglish
Article number6342
JournalNature Communications
Volume6
DOIs
Publication statusPublished - 2015

Keywords

  • butyrate-producing bacteria
  • resistant starch
  • colon-cancer
  • cell-proliferation
  • phylogenetic microarray
  • microbial metabolites
  • intestinal-mucosa
  • epithelial-cells
  • gene-expression
  • human feces

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  • Projects

    MICROBESINSIDE: Exploitation of Our Intestinal Microbiota

    1/06/1031/05/15

    Project: EU research project

    Cite this

    O'Keefe, S. J., Li, J. V., Lahti, L. M., Ou, J., Carbonero, F., Mohammed, K., Posma, J. M., Kinross, J., Wahl, E., Ruder, E., Vipperla, K., Naidoo, V., Mtshali, L., Tims, S., Puylaert, P. G. B., DeLany, J., Krasinskas, A., Benefiel, A. C., Kaseb, H. O., ... Zoetendal, E. G. (2015). Fat, fibre and cancer risk in African Americans and rural Africans. Nature Communications, 6, [6342]. https://doi.org/10.1038/ncomms7342