Fat, fibre and cancer risk in African Americans and rural Africans

S.J. O'Keefe; J.V. Li; L.M. Lahti; J. Ou; F. Carbonero; K. Mohammed; J.M. Posma; J. Kinross; E. Wahl; E. Ruder; K. Vipperla; V. Naidoo; L. Mtshali; S. Tims; P.G.B. Puylaert; J. DeLany; A. Krasinskas; A.C. Benefiel; H.O. Kaseb; K. Newton; J.K. Nicholson; W.M. de Vos; H.R. Gaskins; E.G. Zoetendal

doi:10.1038/ncomms7342

Fat, fibre and cancer risk in African Americans and rural Africans

S.J. O'Keefe^*, J.V. Li, L.M. Lahti, J. Ou, F. Carbonero, K. Mohammed, J.M. Posma, J. Kinross, E. Wahl, E. Ruder, K. Vipperla, V. Naidoo, L. Mtshali, S. Tims, P.G.B. Puylaert, J. DeLany, A. Krasinskas, A.C. Benefiel, H.O. Kaseb, K. NewtonJ.K. Nicholson, W.M. de Vos, H.R. Gaskins, E.G. Zoetendal

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

753 Citations (Scopus)

Abstract

Rates of colon cancer are much higher in African Americans (65:100,000) than in rural South Africans (

Original language	English
Article number	6342
Journal	Nature Communications
Volume	6
DOIs	https://doi.org/10.1038/ncomms7342
Publication status	Published - 2015

Keywords

butyrate-producing bacteria
resistant starch
colon-cancer
cell-proliferation
phylogenetic microarray
microbial metabolites
intestinal-mucosa
epithelial-cells
gene-expression
human feces

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/ncomms7342

MICROBESINSIDE: Exploitation of Our Intestinal Microbiota
1/06/10 → 31/05/15
Project: EU research project

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O'Keefe, S. J., Li, J. V., Lahti, L. M., Ou, J., Carbonero, F., Mohammed, K., Posma, J. M., Kinross, J., Wahl, E., Ruder, E., Vipperla, K., Naidoo, V., Mtshali, L., Tims, S., Puylaert, P. G. B., DeLany, J., Krasinskas, A., Benefiel, A. C., Kaseb, H. O., ... Zoetendal, E. G. (2015). Fat, fibre and cancer risk in African Americans and rural Africans. Nature Communications, 6, Article 6342. https://doi.org/10.1038/ncomms7342

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title = "Fat, fibre and cancer risk in African Americans and rural Africans",

abstract = "Rates of colon cancer are much higher in African Americans (65:100,000) than in rural South Africans (",

keywords = "butyrate-producing bacteria, resistant starch, colon-cancer, cell-proliferation, phylogenetic microarray, microbial metabolites, intestinal-mucosa, epithelial-cells, gene-expression, human feces",

author = "S.J. O'Keefe and J.V. Li and L.M. Lahti and J. Ou and F. Carbonero and K. Mohammed and J.M. Posma and J. Kinross and E. Wahl and E. Ruder and K. Vipperla and V. Naidoo and L. Mtshali and S. Tims and P.G.B. Puylaert and J. DeLany and A. Krasinskas and A.C. Benefiel and H.O. Kaseb and K. Newton and J.K. Nicholson and {de Vos}, W.M. and H.R. Gaskins and E.G. Zoetendal",

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doi = "10.1038/ncomms7342",

language = "English",

volume = "6",

journal = "Nature Communications",

issn = "2041-1723",

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O'Keefe, SJ, Li, JV, Lahti, LM, Ou, J, Carbonero, F, Mohammed, K, Posma, JM, Kinross, J, Wahl, E, Ruder, E, Vipperla, K, Naidoo, V, Mtshali, L, Tims, S, Puylaert, PGB, DeLany, J, Krasinskas, A, Benefiel, AC, Kaseb, HO, Newton, K, Nicholson, JK, de Vos, WM, Gaskins, HR & Zoetendal, EG 2015, 'Fat, fibre and cancer risk in African Americans and rural Africans', Nature Communications, vol. 6, 6342. https://doi.org/10.1038/ncomms7342

TY - JOUR

T1 - Fat, fibre and cancer risk in African Americans and rural Africans

AU - O'Keefe, S.J.

AU - Li, J.V.

AU - Lahti, L.M.

AU - Ou, J.

AU - Carbonero, F.

AU - Mohammed, K.

AU - Posma, J.M.

AU - Kinross, J.

AU - Wahl, E.

AU - Ruder, E.

AU - Vipperla, K.

AU - Naidoo, V.

AU - Mtshali, L.

AU - Tims, S.

AU - Puylaert, P.G.B.

AU - DeLany, J.

AU - Krasinskas, A.

AU - Benefiel, A.C.

AU - Kaseb, H.O.

AU - Newton, K.

AU - Nicholson, J.K.

AU - de Vos, W.M.

AU - Gaskins, H.R.

AU - Zoetendal, E.G.

PY - 2015

Y1 - 2015

N2 - Rates of colon cancer are much higher in African Americans (65:100,000) than in rural South Africans (

AB - Rates of colon cancer are much higher in African Americans (65:100,000) than in rural South Africans (

KW - butyrate-producing bacteria

KW - resistant starch

KW - colon-cancer

KW - cell-proliferation

KW - phylogenetic microarray

KW - microbial metabolites

KW - intestinal-mucosa

KW - epithelial-cells

KW - gene-expression

KW - human feces

U2 - 10.1038/ncomms7342

DO - 10.1038/ncomms7342

M3 - Article

SN - 2041-1723

VL - 6

JO - Nature Communications

JF - Nature Communications

M1 - 6342

ER -

Fat, fibre and cancer risk in African Americans and rural Africans

Abstract

Keywords

UN SDGs

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Projects

MICROBESINSIDE: Exploitation of Our Intestinal Microbiota

Cite this