Exposure assessment of cattle via roughages to plants producing compounds of concern

L.W.D. van Raamsdonk*, W.A. Ozinga, L.A.P. Hoogenboom, P.P.J. Mulder, J.G.J. Mol, M.J. Groot, H.J. van der Fels, W.C.M. de Nijs

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)


Food producing animals are exposed to biologically active plant compounds through feed and roughages, presenting a potential risk to the animal but also consumers of food of animal origin. To evaluate to which plant compounds of concern dairy cows in the Netherlands are exposed, a ranking filter model was developed, combining information on abundance of plant species in vegetation plots in the Netherlands (183,905 plots of three different vegetation types) with plant-compound combinations (700), and with consumption data of fresh grass, grass silage and corn silage by cattle. The most abundant plant genera are those producing cyanogenic glycosides, coumarins and benzofuranocoumarins, being predominantly fodder plants (alfalfa, clover and some grasses) considered to be safe. Highest exposures were estimated for plant genera producing piperidine alkaloids (horsetail), furanocoumarins (parsley and relatives), pyrrolizidine alkaloids (Symphytum, Senecio, Leucanthemum, Eupatorium) and essential oils. The current results allow to prioritise future scientific research on these compounds.
Original languageEnglish
Pages (from-to)27-37
JournalFood Chemistry
Publication statusPublished - 2015


  • Cattle
  • Essential oils
  • Free grazing
  • Furanocoumarins
  • Piperidine alkaloids
  • Plant toxins
  • Pyrrolizidine alkaloids
  • Ranking filter model
  • Roughage
  • Vegetation analysis


Dive into the research topics of 'Exposure assessment of cattle via roughages to plants producing compounds of concern'. Together they form a unique fingerprint.

Cite this