Exopolysaccharides synthesized by Bifidobacterium animalis subsp. lactis interact with TLR4 in intestinal epithelial cells

Nuria Castro-Bravo, Abelardo Margolles, Jerry M. Wells, Patricia Ruas-Madiedo*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Abstract

The toll-like receptors involved in recognition of the exopolysaccharide produced by two isogenic, ropy and non-ropy, Bifidobacterium animalis subsp. lactis strains were investigated. Both strains interact with human embryonic kidney (HEK)-293 cells via TLR2, whereas purified EPSs specifically stimulate TLR4 regardless their molar mass.

Original languageEnglish
Pages (from-to)98-101
Number of pages4
JournalAnaerobe
Volume56
DOIs
Publication statusPublished - 1 Apr 2019

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