Evolution of vascular plants through redeployment of ancient developmental regulators

Kuan Ju Lu, Nicole van’t Wout Hofland, Eliana Mor, Sumanth Mutte, Paul Abrahams, Hirotaka Kato, Klaas Vandepoele, Dolf Weijers*, Bert de Rybel

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Vascular plants provide most of the biomass, food, and feed on earth, yet the molecular innovations that led to the evolution of their conductive tissues are unknown. Here, we reveal the evolutionary trajectory for the heterodimeric TMO5/LHW transcription factor complex, which is rate-limiting for vascular cell proliferation in Arabidopsis thaliana. Both regulators have origins predating vascular tissue emergence, and even terrestrialization. We further show that TMO5 evolved its modern function, including dimerization with LHW, at the origin of land plants. A second innovation in LHW, coinciding with vascular plant emergence, conditioned obligate heterodimerization and generated the critical function in vascular development in Arabidopsis. In summary, our results suggest that the division potential of vascular cells may have been an important factor contributing to the evolution of vascular plants.

Original languageEnglish
Pages (from-to)733-740
Number of pages8
JournalProceedings of the National Academy of Sciences of the United States of America
Volume117
Issue number1
DOIs
Publication statusPublished - 7 Jan 2020

Fingerprint

Blood Vessels
Arabidopsis
Embryophyta
Dimerization
Biomass
Transcription Factors
Cell Proliferation
Food

Keywords

  • Heterodimerization
  • Plant evolution
  • Plant vascular tissues
  • TMO5/LHW
  • Tracheophytes

Cite this

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title = "Evolution of vascular plants through redeployment of ancient developmental regulators",
abstract = "Vascular plants provide most of the biomass, food, and feed on earth, yet the molecular innovations that led to the evolution of their conductive tissues are unknown. Here, we reveal the evolutionary trajectory for the heterodimeric TMO5/LHW transcription factor complex, which is rate-limiting for vascular cell proliferation in Arabidopsis thaliana. Both regulators have origins predating vascular tissue emergence, and even terrestrialization. We further show that TMO5 evolved its modern function, including dimerization with LHW, at the origin of land plants. A second innovation in LHW, coinciding with vascular plant emergence, conditioned obligate heterodimerization and generated the critical function in vascular development in Arabidopsis. In summary, our results suggest that the division potential of vascular cells may have been an important factor contributing to the evolution of vascular plants.",
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Evolution of vascular plants through redeployment of ancient developmental regulators. / Lu, Kuan Ju; van’t Wout Hofland, Nicole; Mor, Eliana; Mutte, Sumanth; Abrahams, Paul; Kato, Hirotaka; Vandepoele, Klaas; Weijers, Dolf; de Rybel, Bert.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 1, 07.01.2020, p. 733-740.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Mutte, Sumanth

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AU - Vandepoele, Klaas

AU - Weijers, Dolf

AU - de Rybel, Bert

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AB - Vascular plants provide most of the biomass, food, and feed on earth, yet the molecular innovations that led to the evolution of their conductive tissues are unknown. Here, we reveal the evolutionary trajectory for the heterodimeric TMO5/LHW transcription factor complex, which is rate-limiting for vascular cell proliferation in Arabidopsis thaliana. Both regulators have origins predating vascular tissue emergence, and even terrestrialization. We further show that TMO5 evolved its modern function, including dimerization with LHW, at the origin of land plants. A second innovation in LHW, coinciding with vascular plant emergence, conditioned obligate heterodimerization and generated the critical function in vascular development in Arabidopsis. In summary, our results suggest that the division potential of vascular cells may have been an important factor contributing to the evolution of vascular plants.

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