Evaluating changes of writhe in computer simulations of supercoiled DNA

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)

Abstract

We compute changes in the writhe of a polygonal space curve when one of the vertices is displaced. The resulting expressions can be used in simulations of supercoiled DNA. For Brownian dynamics simulations, the expressions can be used to eliminate the explicit twisting degree of freedom. For Monte Carlo simulations, they can be used in fast local moves. Preliminary Monte Carlo simulations using only such fast local moves show that these can be used to efficiently simulate small DNA supercoils.
Original languageEnglish
Pages (from-to)1-5
JournalJournal of Chemical Physics
Volume122
Issue number6
DOIs
Publication statusPublished - 2005

Keywords

  • dynamics
  • number
  • chain

Fingerprint Dive into the research topics of 'Evaluating changes of writhe in computer simulations of supercoiled DNA'. Together they form a unique fingerprint.

  • Cite this