Wageningen Food Safety Research is EU Reference Laboratory (EURL)
for mycotoxins & plant toxins in food and feed. The EURL must ensure
comparability and reliability of National Reference Laboratories
(NRLs), assigned by each EU member state. One tool for this is to
organise proficiency tests (PT).
The PT described here was organised in 2018 for the quantitative
determination of deoxynivalenol (DON), 3-acetyl-DON, 15-acetyl-
DON, and DON-3-glucoside (DON-3G).
Relevant levels: currently only DON is regulated. Maximum limits for
food range from 200-1750 μg/kg, for feed guidance levels of 0.9-12
mg/kg apply. For risk assessment, besides DON, the measurement of
the acetyl-DONs and DON-3G is recommended by EFSA since they
contribute to the overall exposure. Target LOQs for this purpose are
50-100 μg/kg for DON, and 10-20 μg/kg for the DON conjugates.