Establishing Guidelines to Retain Viability of Probiotics during Spray Drying

J.A. Perdana, M.B. Fox, R.M. Boom, M.A.I. Schutyser*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)


We present the application of a model-based approach to map processing conditions suitable to spray dry probiotics with minimal viability loss. The approach combines the drying history and bacterial inactivation kinetics to predict the retention of viability after drying. The approach was used to systematically assess the influence of operational co-current spray drying conditions on residual viability. Moreover, two promising alternative drying strategies for probiotics were evaluated involving encapsulation in a hollow particle and using an ‘ideal-mixed’ dryer system. Finally, a graph was constructed with the model to provide visual guidelines to optimize spray dying for probiotics in terms of viability and drying efficiency.
Original languageEnglish
Pages (from-to)1560-1569
JournalDrying Technology
Issue number13
Publication statusPublished - 2015


  • lactobacillus-plantarum wcfs1
  • inactivation
  • integration
  • isotherms
  • products
  • sorption
  • storage
  • trends
  • foods
  • model


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