Enhancement of the Adhesive Properties by Optimizing the Water Content in PNIPAM-Functionalized Complex Coacervates

Marco Dompé; Mehdi Vahdati; Froukje Van Ligten; Francisco J. Cedano-Serrano; Dominique Hourdet; Costantino Creton; Marco Zanetti; Pierangiola Bracco; Jasper Van Der Gucht; Thomas Kodger; Marleen Kamperman

doi:10.1021/acsapm.0c00185

Enhancement of the Adhesive Properties by Optimizing the Water Content in PNIPAM-Functionalized Complex Coacervates

Marco Dompé, Mehdi Vahdati, Froukje Van Ligten, Francisco J. Cedano-Serrano, Dominique Hourdet, Costantino Creton, Marco Zanetti, Pierangiola Bracco, Jasper Van Der Gucht, Thomas Kodger, Marleen Kamperman^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

11 Citations (Scopus)

Abstract

Most commercially available soft tissue glues offer poor performance in the human body. We have developed an injectable adhesive whose setting mechanism is activated by a change in environmental factors, i.e., temperature and/or ionic strength. The material and setting process are inspired by the adhesive processing mechanism observed in natural maritime glues. Complex coacervation, a liquid–liquid phase separation between oppositely charged polyelectrolytes, is thought to play an important role in the processing. Complex coacervates are characterized by a high water content, which inevitably weakens the glue. Here, we aim to increase the adhesive performance by systematically tuning the water content. Among the several strategies here explored, the most effective one is the mechanical removal of water using an extruder, resulting in an increase of work of adhesion by 1 order of magnitude compared to the original formulation.

Original language	English
Pages (from-to)	1722-1730
Journal	ACS Applied Polymer Materials
Volume	2
Issue number	4
DOIs	https://doi.org/10.1021/acsapm.0c00185
Publication status	Published - 10 Apr 2020

Keywords

bioinspired adhesives
complex coacervation
extrusion
underwater adhesion
water content

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10.1021/acsapm.0c00185Licence: CC BY-NC-ND

https://edepot.wur.nl/538025Licence: CC BY-NC-ND

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BioSmartTrainee: Training in Bio-Inspired Design of Smart Adhesive Materials
1/10/15 → 30/09/19
Project: EU research project

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Dompé, M., Vahdati, M., Van Ligten, F., Cedano-Serrano, F. J., Hourdet, D., Creton, C., Zanetti, M., Bracco, P., Van Der Gucht, J., Kodger, T., & Kamperman, M. (2020). Enhancement of the Adhesive Properties by Optimizing the Water Content in PNIPAM-Functionalized Complex Coacervates. ACS Applied Polymer Materials, 2(4), 1722-1730. https://doi.org/10.1021/acsapm.0c00185

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title = "Enhancement of the Adhesive Properties by Optimizing the Water Content in PNIPAM-Functionalized Complex Coacervates",

abstract = "Most commercially available soft tissue glues offer poor performance in the human body. We have developed an injectable adhesive whose setting mechanism is activated by a change in environmental factors, i.e., temperature and/or ionic strength. The material and setting process are inspired by the adhesive processing mechanism observed in natural maritime glues. Complex coacervation, a liquid–liquid phase separation between oppositely charged polyelectrolytes, is thought to play an important role in the processing. Complex coacervates are characterized by a high water content, which inevitably weakens the glue. Here, we aim to increase the adhesive performance by systematically tuning the water content. Among the several strategies here explored, the most effective one is the mechanical removal of water using an extruder, resulting in an increase of work of adhesion by 1 order of magnitude compared to the original formulation.",

keywords = "bioinspired adhesives, complex coacervation, extrusion, underwater adhesion, water content",

author = "Marco Domp{\'e} and Mehdi Vahdati and {Van Ligten}, Froukje and Cedano-Serrano, {Francisco J.} and Dominique Hourdet and Costantino Creton and Marco Zanetti and Pierangiola Bracco and {Van Der Gucht}, Jasper and Thomas Kodger and Marleen Kamperman",

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doi = "10.1021/acsapm.0c00185",

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Dompé, M, Vahdati, M, Van Ligten, F, Cedano-Serrano, FJ, Hourdet, D, Creton, C, Zanetti, M, Bracco, P, Van Der Gucht, J , Kodger, T & Kamperman, M 2020, 'Enhancement of the Adhesive Properties by Optimizing the Water Content in PNIPAM-Functionalized Complex Coacervates', ACS Applied Polymer Materials, vol. 2, no. 4, pp. 1722-1730. https://doi.org/10.1021/acsapm.0c00185

TY - JOUR

T1 - Enhancement of the Adhesive Properties by Optimizing the Water Content in PNIPAM-Functionalized Complex Coacervates

AU - Dompé, Marco

AU - Vahdati, Mehdi

AU - Van Ligten, Froukje

AU - Cedano-Serrano, Francisco J.

AU - Hourdet, Dominique

AU - Creton, Costantino

AU - Zanetti, Marco

AU - Bracco, Pierangiola

AU - Van Der Gucht, Jasper

AU - Kodger, Thomas

AU - Kamperman, Marleen

PY - 2020/4/10

Y1 - 2020/4/10

N2 - Most commercially available soft tissue glues offer poor performance in the human body. We have developed an injectable adhesive whose setting mechanism is activated by a change in environmental factors, i.e., temperature and/or ionic strength. The material and setting process are inspired by the adhesive processing mechanism observed in natural maritime glues. Complex coacervation, a liquid–liquid phase separation between oppositely charged polyelectrolytes, is thought to play an important role in the processing. Complex coacervates are characterized by a high water content, which inevitably weakens the glue. Here, we aim to increase the adhesive performance by systematically tuning the water content. Among the several strategies here explored, the most effective one is the mechanical removal of water using an extruder, resulting in an increase of work of adhesion by 1 order of magnitude compared to the original formulation.

AB - Most commercially available soft tissue glues offer poor performance in the human body. We have developed an injectable adhesive whose setting mechanism is activated by a change in environmental factors, i.e., temperature and/or ionic strength. The material and setting process are inspired by the adhesive processing mechanism observed in natural maritime glues. Complex coacervation, a liquid–liquid phase separation between oppositely charged polyelectrolytes, is thought to play an important role in the processing. Complex coacervates are characterized by a high water content, which inevitably weakens the glue. Here, we aim to increase the adhesive performance by systematically tuning the water content. Among the several strategies here explored, the most effective one is the mechanical removal of water using an extruder, resulting in an increase of work of adhesion by 1 order of magnitude compared to the original formulation.

KW - bioinspired adhesives

KW - complex coacervation

KW - extrusion

KW - underwater adhesion

KW - water content

U2 - 10.1021/acsapm.0c00185

DO - 10.1021/acsapm.0c00185

M3 - Article

VL - 2

SP - 1722

EP - 1730

JO - ACS Applied Polymer Materials

JF - ACS Applied Polymer Materials

SN - 2637-6105

IS - 4

ER -

Enhancement of the Adhesive Properties by Optimizing the Water Content in PNIPAM-Functionalized Complex Coacervates

Abstract

Keywords

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BioSmartTrainee: Training in Bio-Inspired Design of Smart Adhesive Materials

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