Endogenous human milk Peptide release is greater after preterm birth than term birth

D.C. Dallas, C.J. Smink, R.C. Robinson, T. Tian, A. Guerrero, E.A. Parker, J.T. Smilowitz, K.A. Hettinga, M.A. Underwood, C.B. Lebrilla, J.B. German, D. Barile

Research output: Contribution to journalArticleAcademicpeer-review

34 Citations (Scopus)

Abstract

Background: Hundreds of naturally occurring milk peptides are present in term human milk. Preterm milk is produced before complete maturation of the mammary gland, which could change milk synthesis and secretion processes within the mammary gland, leading to differences in protein expression and enzymatic activity, thereby resulting in an altered peptide profile. Objective: This study examined differences in peptides present between milk from women delivering at term and women delivering prematurely.
LanguageEnglish
Pages425-433
JournalThe Journal of Nutrition
Volume145
Issue number3
DOIs
Publication statusPublished - 2015

Fingerprint

Term Birth
Premature Birth
Human Milk
Milk
Peptides
Human Mammary Glands
Secretory Pathway
Proteins

Keywords

  • breast-milk
  • bioactive peptides
  • plasmin activity
  • early lactation
  • casein
  • enzyme
  • proteins
  • infants
  • trypsin
  • carboxypeptidase

Cite this

Dallas, D. C., Smink, C. J., Robinson, R. C., Tian, T., Guerrero, A., Parker, E. A., ... Barile, D. (2015). Endogenous human milk Peptide release is greater after preterm birth than term birth. The Journal of Nutrition, 145(3), 425-433. https://doi.org/10.3945/jn.114.203646
Dallas, D.C. ; Smink, C.J. ; Robinson, R.C. ; Tian, T. ; Guerrero, A. ; Parker, E.A. ; Smilowitz, J.T. ; Hettinga, K.A. ; Underwood, M.A. ; Lebrilla, C.B. ; German, J.B. ; Barile, D. / Endogenous human milk Peptide release is greater after preterm birth than term birth. In: The Journal of Nutrition. 2015 ; Vol. 145, No. 3. pp. 425-433.
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Dallas, DC, Smink, CJ, Robinson, RC, Tian, T, Guerrero, A, Parker, EA, Smilowitz, JT, Hettinga, KA, Underwood, MA, Lebrilla, CB, German, JB & Barile, D 2015, 'Endogenous human milk Peptide release is greater after preterm birth than term birth', The Journal of Nutrition, vol. 145, no. 3, pp. 425-433. https://doi.org/10.3945/jn.114.203646

Endogenous human milk Peptide release is greater after preterm birth than term birth. / Dallas, D.C.; Smink, C.J.; Robinson, R.C.; Tian, T.; Guerrero, A.; Parker, E.A.; Smilowitz, J.T.; Hettinga, K.A.; Underwood, M.A.; Lebrilla, C.B.; German, J.B.; Barile, D.

In: The Journal of Nutrition, Vol. 145, No. 3, 2015, p. 425-433.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Smink, C.J.

AU - Robinson, R.C.

AU - Tian, T.

AU - Guerrero, A.

AU - Parker, E.A.

AU - Smilowitz, J.T.

AU - Hettinga, K.A.

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AU - Barile, D.

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KW - bioactive peptides

KW - plasmin activity

KW - early lactation

KW - casein

KW - enzyme

KW - proteins

KW - infants

KW - trypsin

KW - carboxypeptidase

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