Encapsulation of active ingredients

K.F. Gotlieb (Inventor), R.J.G. van Schijndel (Inventor), J.J.G. van Soest (Inventor)

    Research output: PatentOther research output


    Microspheres having a particle size of 50 nm to 1 nm and a polydispersity of less than 40%, consisting of a chemically cross-linked starch shell containing an active ingredient, are obtained by preparing an oil-in-water emulsion of the active ingredient in a hydrophobic phase and starch or a dispersion of a solid active ingredient and starch in water, incorporating the oil-in-water emulsion or solid dispersion in an outer hydrophobic phase, particles of the oil-in-water emulsion or solid dispersion being formed in the outer hydrophobic phase, cross-linking the starch or derivative thereof and removing the outer hydrophobic phase if desired.
    Original languageEnglish
    Patent numberWO9901214
    Priority date1/07/97
    Publication statusPublished - 14 Jan 1999

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