Effects of sucrose on salivary flow and composition: differences between real and sham intake

L.F. Harthoorn, C.R. Brattinga, C. van Kekem, E. Neyraud, E. Dransfield

    Research output: Contribution to journalArticleAcademicpeer-review

    12 Citations (Scopus)

    Abstract

    Human saliva contains numerous salivary components that are fundamental for a healthy oral environment and the oral processing of foods. To study a possible differential influence of orosensory stimulation and metabolic activation on salivary composition, human parotid salivary flow, pH, A280, and agr-amylase activity were measured before, during and after real or sham (sip-and-spit) sucrose intakes. Variations in these salivary characteristics were related to perceived satiety. Sucrose, as either real or sham intake, increased salivary flow and pH and decreased A280 before returning to pre-intake levels. Increased salivation was dependent on the sucrose concentration and was accompanied with a higher pH and lower A280. After sucrose ingestion, the salivary agr-amylase activity increased, while no increase occurred after sham sucrose intake. Similarly, rated satiety increased with real but not by sham sucrose intake. This indicated that salivary agr-amylase is associated with perceived satiety controlled by caloric perception downstream of the oral cavity.
    Original languageEnglish
    Pages (from-to)637-646
    JournalInternational Journal of Food Sciences and Nutrition
    Volume60
    Issue number8
    DOIs
    Publication statusPublished - 2009

    Keywords

    • alpha-amylase secretion
    • sympathetic activity
    • flavor preferences
    • perceived satiety
    • sweet taste
    • stimulation
    • mastication
    • expression
    • glands
    • humans

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