Effect of different scenarios for selective dry-cow therapy on udder health, antimicrobial usage, and economics

C.G.M. Scherpenzeel, I.E.M. den Uijl, G. van Schaik, Olde R.G.M. Riekerink, H. Hogeveen, T.J.G.M. Lam

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)

Abstract

The goal of dry-cow therapy (DCT) is to reduce the prevalence of intramammary infections (IMI) by eliminating existing IMI at drying off and preventing new IMI from occurring during the dry period. Due to public health concerns, however, preventive use of antimicrobials has become questionable. In this study, we evaluated the effects of 8 scenarios for selecting animals for DCT, taking into account variation in parity and cow-level somatic cell count (SCC) at drying off. The aim of this study was to evaluate udder health, antimicrobial usage, and economics at the herd level when using different scenarios for selecting cows for DCT. To enable calculation and comparison of the effects of different scenarios to select cows for DCT in an "average" herd, we created an example herd, with a virtual herd size of 100 dairy cows to be calving during a year. Udder health, antimicrobial usage, and economics were evaluated during the dry period and the first 100 d in lactation, the period during which the greatest effect of DCT is expected. This leads to an estimated 13,551 cow-days at risk during a year in a 100-cow dairy herd. In addition to a blanket DCT (BDCT) scenario, we developed 7 scenarios to select cows for DCT based on SCC. The scenarios covered a range of possible approaches to select low-SCC cows for DCT, all based on cow-level SCC thresholds on the last milk recording before drying off. The incidence rate of clinical mastitis in the example herd varied from 11.6 to 14.5 cases of clinical mastitis per 10,000 cow-days at risk in the different scenarios, and the prevalence of subclinical mastitis varied from 38.8% in scenario 1 (BDCT) to 48.3% in scenario 8. Total antimicrobial usage for DCT and clinical mastitis treatment varied over the scenarios from 1.27 (scenario 8) to 3.15 animal daily dosages (BDCT), leading to a maximum reduction in antimicrobial usage of 60% for scenario 8 compared with BDCT. The total costs for each of the scenarios showed little variation, varying from €4,893 for scenario 5 to €5,383 for scenario 8. The effect of selective DCT compared with BDCT on udder health, antimicrobial usage, and economics is influenced by the SCC criteria used to select cows for DCT. Scenario 2 resulted in the lowest increases in clinical and subclinical mastitis compared with BDCT. The greatest reduction in antimicrobial usage was achieved under scenario 8. From an economic perspective, lowest costs were achieved with scenario 5. Drying off dairy cows with antimicrobials has an effect on udder health, antimicrobial usage, and economics.

Original languageEnglish
Pages (from-to)3753-3764
JournalJournal of Dairy Science
Volume99
Issue number5
DOIs
Publication statusPublished - 2016

Fingerprint

Animal Mammary Glands
udders
anti-infective agents
Economics
cows
economics
therapeutics
Health
Mastitis
Cell Count
Therapeutics
somatic cell count
mastitis
drying
herds
Infection
dry period (lactation)
Costs and Cost Analysis
Parity
Lactation

Keywords

  • Antimicrobial reduction
  • Dry-cow therapy
  • Economics
  • Mastitis

Cite this

Scherpenzeel, C. G. M., den Uijl, I. E. M., van Schaik, G., Riekerink, O. R. G. M., Hogeveen, H., & Lam, T. J. G. M. (2016). Effect of different scenarios for selective dry-cow therapy on udder health, antimicrobial usage, and economics. Journal of Dairy Science, 99(5), 3753-3764. https://doi.org/10.3168/jds.2015-9963
Scherpenzeel, C.G.M. ; den Uijl, I.E.M. ; van Schaik, G. ; Riekerink, Olde R.G.M. ; Hogeveen, H. ; Lam, T.J.G.M. / Effect of different scenarios for selective dry-cow therapy on udder health, antimicrobial usage, and economics. In: Journal of Dairy Science. 2016 ; Vol. 99, No. 5. pp. 3753-3764.
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Effect of different scenarios for selective dry-cow therapy on udder health, antimicrobial usage, and economics. / Scherpenzeel, C.G.M.; den Uijl, I.E.M.; van Schaik, G.; Riekerink, Olde R.G.M.; Hogeveen, H.; Lam, T.J.G.M.

In: Journal of Dairy Science, Vol. 99, No. 5, 2016, p. 3753-3764.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Effect of different scenarios for selective dry-cow therapy on udder health, antimicrobial usage, and economics

AU - Scherpenzeel, C.G.M.

AU - den Uijl, I.E.M.

AU - van Schaik, G.

AU - Riekerink, Olde R.G.M.

AU - Hogeveen, H.

AU - Lam, T.J.G.M.

PY - 2016

Y1 - 2016

N2 - The goal of dry-cow therapy (DCT) is to reduce the prevalence of intramammary infections (IMI) by eliminating existing IMI at drying off and preventing new IMI from occurring during the dry period. Due to public health concerns, however, preventive use of antimicrobials has become questionable. In this study, we evaluated the effects of 8 scenarios for selecting animals for DCT, taking into account variation in parity and cow-level somatic cell count (SCC) at drying off. The aim of this study was to evaluate udder health, antimicrobial usage, and economics at the herd level when using different scenarios for selecting cows for DCT. To enable calculation and comparison of the effects of different scenarios to select cows for DCT in an "average" herd, we created an example herd, with a virtual herd size of 100 dairy cows to be calving during a year. Udder health, antimicrobial usage, and economics were evaluated during the dry period and the first 100 d in lactation, the period during which the greatest effect of DCT is expected. This leads to an estimated 13,551 cow-days at risk during a year in a 100-cow dairy herd. In addition to a blanket DCT (BDCT) scenario, we developed 7 scenarios to select cows for DCT based on SCC. The scenarios covered a range of possible approaches to select low-SCC cows for DCT, all based on cow-level SCC thresholds on the last milk recording before drying off. The incidence rate of clinical mastitis in the example herd varied from 11.6 to 14.5 cases of clinical mastitis per 10,000 cow-days at risk in the different scenarios, and the prevalence of subclinical mastitis varied from 38.8% in scenario 1 (BDCT) to 48.3% in scenario 8. Total antimicrobial usage for DCT and clinical mastitis treatment varied over the scenarios from 1.27 (scenario 8) to 3.15 animal daily dosages (BDCT), leading to a maximum reduction in antimicrobial usage of 60% for scenario 8 compared with BDCT. The total costs for each of the scenarios showed little variation, varying from €4,893 for scenario 5 to €5,383 for scenario 8. The effect of selective DCT compared with BDCT on udder health, antimicrobial usage, and economics is influenced by the SCC criteria used to select cows for DCT. Scenario 2 resulted in the lowest increases in clinical and subclinical mastitis compared with BDCT. The greatest reduction in antimicrobial usage was achieved under scenario 8. From an economic perspective, lowest costs were achieved with scenario 5. Drying off dairy cows with antimicrobials has an effect on udder health, antimicrobial usage, and economics.

AB - The goal of dry-cow therapy (DCT) is to reduce the prevalence of intramammary infections (IMI) by eliminating existing IMI at drying off and preventing new IMI from occurring during the dry period. Due to public health concerns, however, preventive use of antimicrobials has become questionable. In this study, we evaluated the effects of 8 scenarios for selecting animals for DCT, taking into account variation in parity and cow-level somatic cell count (SCC) at drying off. The aim of this study was to evaluate udder health, antimicrobial usage, and economics at the herd level when using different scenarios for selecting cows for DCT. To enable calculation and comparison of the effects of different scenarios to select cows for DCT in an "average" herd, we created an example herd, with a virtual herd size of 100 dairy cows to be calving during a year. Udder health, antimicrobial usage, and economics were evaluated during the dry period and the first 100 d in lactation, the period during which the greatest effect of DCT is expected. This leads to an estimated 13,551 cow-days at risk during a year in a 100-cow dairy herd. In addition to a blanket DCT (BDCT) scenario, we developed 7 scenarios to select cows for DCT based on SCC. The scenarios covered a range of possible approaches to select low-SCC cows for DCT, all based on cow-level SCC thresholds on the last milk recording before drying off. The incidence rate of clinical mastitis in the example herd varied from 11.6 to 14.5 cases of clinical mastitis per 10,000 cow-days at risk in the different scenarios, and the prevalence of subclinical mastitis varied from 38.8% in scenario 1 (BDCT) to 48.3% in scenario 8. Total antimicrobial usage for DCT and clinical mastitis treatment varied over the scenarios from 1.27 (scenario 8) to 3.15 animal daily dosages (BDCT), leading to a maximum reduction in antimicrobial usage of 60% for scenario 8 compared with BDCT. The total costs for each of the scenarios showed little variation, varying from €4,893 for scenario 5 to €5,383 for scenario 8. The effect of selective DCT compared with BDCT on udder health, antimicrobial usage, and economics is influenced by the SCC criteria used to select cows for DCT. Scenario 2 resulted in the lowest increases in clinical and subclinical mastitis compared with BDCT. The greatest reduction in antimicrobial usage was achieved under scenario 8. From an economic perspective, lowest costs were achieved with scenario 5. Drying off dairy cows with antimicrobials has an effect on udder health, antimicrobial usage, and economics.

KW - Antimicrobial reduction

KW - Dry-cow therapy

KW - Economics

KW - Mastitis

U2 - 10.3168/jds.2015-9963

DO - 10.3168/jds.2015-9963

M3 - Article

VL - 99

SP - 3753

EP - 3764

JO - Journal of Dairy Science

JF - Journal of Dairy Science

SN - 0022-0302

IS - 5

ER -