Results of spray drift experiments are reported of the H.S.S. CF Intelligent Spray Application (I.S.A.) precision orchard crossflow fan sprayer. The H.S.S. CF I.S.A. is a precision cross-flow fan orchard sprayer equipped with sensors for green leaf detection and Pulse Width Modulation (PWM) modules at the nozzle-bodies for precise and variable dosing. The H.S.S. CF I.S.A. precision cross-flow fan orchard sprayer equipped with PWM operating nozzles, Lechler IDK 90-015 C flat fan venturi nozzles (75% drift reduction), low air setting (1400 rpm fan) and green leaf detection sensors and single- sided spraying of the outside tree row obtains a spray drift reduction of 99.0% at 4½-5½ m distance from the last tree row compared to the reference spray system for fruit crop spraying in the Netherlands. Measurement of airborne spray drift averaged over 0-10 m height at 7.5 m distance from the last tree row resulted in a spray drift reduction of 97.6% when spraying with the H.S.S. CF I.S.A. precision orchard sprayer.