Draft genome sequence of a porcine commensal, Rothia nasimurium, encoding a nonribosomal peptide synthetase predicted to produce the ionophore antibiotic valinomycin

Rogier A. Gaiser, Marnix H. Medema, Michiel Kleerebezem, Peter van Baarlen, Jerry M. Wells*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

We report the draft whole-genome sequence of Rothia nasimurium isolated from a porcine tonsil. The genome encodes a nonribosomal peptide synthetase predicted to produce valinomycin, a cyclic dodecadepsipeptide ionophore. Previously, valinomycin was known to be produced only by Streptomyces species and isolates belonging to the Bacillus pumilus group.

Original languageEnglish
Article numbere00453-17
Number of pages2
JournalGenome Announcements
Volume5
Issue number22
DOIs
Publication statusPublished - 2017

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Peptide Synthases
Valinomycin
Ionophores
Swine
Genome
Anti-Bacterial Agents
Palatine Tonsil
Streptomyces
Bacillus pumilus

Cite this

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title = "Draft genome sequence of a porcine commensal, Rothia nasimurium, encoding a nonribosomal peptide synthetase predicted to produce the ionophore antibiotic valinomycin",
abstract = "We report the draft whole-genome sequence of Rothia nasimurium isolated from a porcine tonsil. The genome encodes a nonribosomal peptide synthetase predicted to produce valinomycin, a cyclic dodecadepsipeptide ionophore. Previously, valinomycin was known to be produced only by Streptomyces species and isolates belonging to the Bacillus pumilus group.",
author = "Gaiser, {Rogier A.} and Medema, {Marnix H.} and Michiel Kleerebezem and {van Baarlen}, Peter and Wells, {Jerry M.}",
year = "2017",
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language = "English",
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AU - Gaiser, Rogier A.

AU - Medema, Marnix H.

AU - Kleerebezem, Michiel

AU - van Baarlen, Peter

AU - Wells, Jerry M.

PY - 2017

Y1 - 2017

N2 - We report the draft whole-genome sequence of Rothia nasimurium isolated from a porcine tonsil. The genome encodes a nonribosomal peptide synthetase predicted to produce valinomycin, a cyclic dodecadepsipeptide ionophore. Previously, valinomycin was known to be produced only by Streptomyces species and isolates belonging to the Bacillus pumilus group.

AB - We report the draft whole-genome sequence of Rothia nasimurium isolated from a porcine tonsil. The genome encodes a nonribosomal peptide synthetase predicted to produce valinomycin, a cyclic dodecadepsipeptide ionophore. Previously, valinomycin was known to be produced only by Streptomyces species and isolates belonging to the Bacillus pumilus group.

U2 - 10.1128/genomeA.00453-17

DO - 10.1128/genomeA.00453-17

M3 - Article

VL - 5

JO - Genome Announcements

JF - Genome Announcements

SN - 2169-8287

IS - 22

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ER -