DNA sequences which code for virulence characteristics of Streptococcus suis and parts thereof, polypeptides and antibodies derived therefrom and the use thereof for the diagnosis of and protection against infection by S. suis in mammals, including man

H.E. Smith (Inventor)

Research output: PatentOther research output

Abstract

The invention provides DNA sequences which code for polypeptides which are characteristic for the virulence of the pathogenic bacterium Streptococcus suis and parts thereof, and polypeptides and antibodies derived therefrom. The sequences code for a polypeptide of 90.000-120.000 daltons or a polypeptide of higher molecular weight containing such a polypeptide, and for a polypeptide of 135.000-136.000 daltons (muramidase released protein), or parts thereof. The sequences themselves, and also the polypeptides and antibodies derived therefrom, are used for diagnosis of and protection against infection by S. suis in mammals, including man.
Original languageEnglish
Patent numberWO9216630
Priority date21/03/91
Publication statusPublished - 1 Oct 1992

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