Distribution, Elimination and Toxicity of Silver Nanoparticles and Silver Ions in Rats after 28-day Oral Exposure

M. van der Zande, R.J. Vandebriel, E. Doren, E.H.M. Kramer, Z. Herrera-Rivera, C.S. serrano-Rojero, E.R. Gremmer, J. Mast, R.J.B. Peters, P.C.H. Hollman, P.J.M. Hendriksen, H.J.P. Marvin, A.A.C.M. Peijnenburg, H. Bouwmeester

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Abstract

We report the results of a 28-day oral exposure study in rats, exposed to
Original languageEnglish
Pages (from-to)7427-7442
JournalACS Nano
Volume6
Issue number8
DOIs
Publication statusPublished - 2012

Keywords

  • sprague-dawley rats
  • brain-barrier permeability
  • engineered nanoparticles
  • inhalation toxicity
  • tissue distribution
  • release
  • translocation
  • localization
  • deposition
  • kinetics

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    van der Zande, M., Vandebriel, R. J., Doren, E., Kramer, E. H. M., Herrera-Rivera, Z., serrano-Rojero, C. S., Gremmer, E. R., Mast, J., Peters, R. J. B., Hollman, P. C. H., Hendriksen, P. J. M., Marvin, H. J. P., Peijnenburg, A. A. C. M., & Bouwmeester, H. (2012). Distribution, Elimination and Toxicity of Silver Nanoparticles and Silver Ions in Rats after 28-day Oral Exposure. ACS Nano, 6(8), 7427-7442. https://doi.org/10.1021/nn302649p