Projects per year
Abstract
Vink et al. tracked single CRISPR RNA-surveillance complexes (Cascade) in the native host cell and determined the influence of Cascade copy numbers, PAM scanning speed, and the presence of CRISPR arrays and transcription on their ability to find and clear invading mobile genetic elements from the cell.
Original language | English |
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Pages (from-to) | 39-50.e10 |
Journal | Molecular Cell |
Volume | 77 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2 Jan 2020 |
Keywords
- arms race
- Cascade
- CRISPR-Cas
- PALM
- PAM
- photo-activation localization microscopy
- single molecule
- single-particle tracking
- target search
Fingerprint Dive into the research topics of 'Direct Visualization of Native CRISPR Target Search in Live Bacteria Reveals Cascade DNA Surveillance Mechanism'. Together they form a unique fingerprint.
Projects
- 1 Finished
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REMEMBER: Adaptive immunity in prokaryotes: how Bacteria do not forgive and do not forget their enemies
1/06/15 → 31/05/20
Project: EU research project