Dioxins in Food and Feed - Reference Methods and New Certified Reference Materials (DIFFERENCE)

S.P.J. van Leeuwen, L. Goeyens, J. van Loco, S. Carbonelle, I. van Overmeire, H. Beernaert, R. van Cleuvenbergen, G. Schoeters, E. Bjoerklund, S. Sporring, M. Abalos, E. Abad, J. Rivera, J. Santos, W.A. Traag, R. Hoogenboom, P. Haglund, K. Wiberg, C. von Holst, A. MaquetA.L. Pasini, D. Fraise, G. Becher, P. Korytar, P.E.G. Leonards, J. de Boer

Research output: Book/ReportReportProfessional


The European research project DIFFERENCE (“Dioxins in Food and Feed – Reference methods and New Certified Reference Materials”) was focussed on the development of an alternative methods for analysis of polychlorinated dibenzodioxins (PCDDs), dibenzofurans (PCDFs) and dioxin-like polychlorinated biphenyls (dl-PCBs) using comprehensive multi-dimensional gas chromatography (GC×GC), gas chromatography combined with low resolution ion-trap mass spectrometry (GCLRMS/ MS), the CALUX bioassay and an Ah-PCR technique. GC combined with high resolution mass spectrometry (HRMS) was used as a reference method in all comparisons.
Original languageEnglish
Place of PublicationIJmuiden
Number of pages75
Publication statusPublished - 2005

Publication series

NameReport / RIVO-Netherlands Institute for Fisheries Research
No.no. C022/05


  • dioxins
  • food analysis
  • food safety
  • comparisons
  • reference standards
  • polychlorinated biphenyls
  • polychlorinated dibenzodioxins

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