Different transcriptional response between susceptible and resistant common carp (Cyprinus carpio) fish hints on the mechanism of CyHV-3 disease resistance

Roni Tadmor-Levi, Adi Doron-faigenboim, Evgeniya Marcos-hadad, Jules Petit, Gideon Hulata, Maria Forlenza, Geert F. Wiegertjes, Lior David*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Infectious disease outbreaks form major setbacks to aquaculture production and to further development of this important sector. Cyprinid herpes virus-3 (CyHV-3) is a dsDNA virus widely hampering production of common carp (Cyprinus carpio), one of the most farmed fish species worldwide. Genetically disease resistant strains are highly sought after as a sustainable solution to this problem. To study the genetic basis and cellular pathways underlying disease resistance, RNA-Seq was used to characterize transcriptional responses of susceptible and resistant fish at day 4 after CyHV-3 infection.
Original languageEnglish
Article number1019
JournalBMC Genomics
Volume20
Issue number1
DOIs
Publication statusPublished - 26 Dec 2019

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