Different infection parameters between dairy cows and calves after an infection with foot-and-mouth disease virus

K. Orsel, A. Dekker, J.A. Stegeman, M.C.M. de Jong, A. Bouma

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Abstract

Clinical observations of a foot-and-mouth disease (FMD) virus infection in dairy cows and calves were different. This raised the question whether they would also differ with respect to virus excretion and transmission. Data were available from transmission experiments carried out with groups of dairy cows and calves. Half of each group was inoculated with FMDV O/NED/2001; the other half contact-exposed to inoculated animals. Virus excretion, clinical signs and antibody response were measured and virus transmission was quantified. Infected calves showed mild clinical signs which did not affect general health or appetite, and not all contact calves became infected. Dairy cows, on the other hand, showed severe FMD lesions resulting in clinical mastitis, severe lameness and decreased feed intake. Also fever was observed for three consecutive days. All contact cows became infected and showed the same severity of clinical signs. The total and mean daily virus excretion differed significantly between cows and calves (P <0.05). Possibly, virus replication and clinical manifestation are associated, but the underlying mechanism of these differences needs to be elucidated. We did not observe a significant difference in virus transmission between calves and cows
Original languageEnglish
Pages (from-to)116-118
JournalThe Veterinary Journal
Volume186
Issue number1
DOIs
Publication statusPublished - 2010

Fingerprint

Foot-and-Mouth Disease Virus
dairy calves
Foot-and-mouth disease virus
dairy cows
calves
Viruses
excretion
virus transmission
foot-and-mouth disease
Infection
cows
infection
viruses
Foot-and-Mouth Disease
appetite
virus replication
lameness
lesions (animal)
Mastitis
fever

Keywords

  • transmission
  • vaccination

Cite this

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title = "Different infection parameters between dairy cows and calves after an infection with foot-and-mouth disease virus",
abstract = "Clinical observations of a foot-and-mouth disease (FMD) virus infection in dairy cows and calves were different. This raised the question whether they would also differ with respect to virus excretion and transmission. Data were available from transmission experiments carried out with groups of dairy cows and calves. Half of each group was inoculated with FMDV O/NED/2001; the other half contact-exposed to inoculated animals. Virus excretion, clinical signs and antibody response were measured and virus transmission was quantified. Infected calves showed mild clinical signs which did not affect general health or appetite, and not all contact calves became infected. Dairy cows, on the other hand, showed severe FMD lesions resulting in clinical mastitis, severe lameness and decreased feed intake. Also fever was observed for three consecutive days. All contact cows became infected and showed the same severity of clinical signs. The total and mean daily virus excretion differed significantly between cows and calves (P <0.05). Possibly, virus replication and clinical manifestation are associated, but the underlying mechanism of these differences needs to be elucidated. We did not observe a significant difference in virus transmission between calves and cows",
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Different infection parameters between dairy cows and calves after an infection with foot-and-mouth disease virus. / Orsel, K.; Dekker, A.; Stegeman, J.A.; de Jong, M.C.M.; Bouma, A.

In: The Veterinary Journal, Vol. 186, No. 1, 2010, p. 116-118.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Dekker, A.

AU - Stegeman, J.A.

AU - de Jong, M.C.M.

AU - Bouma, A.

PY - 2010

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AB - Clinical observations of a foot-and-mouth disease (FMD) virus infection in dairy cows and calves were different. This raised the question whether they would also differ with respect to virus excretion and transmission. Data were available from transmission experiments carried out with groups of dairy cows and calves. Half of each group was inoculated with FMDV O/NED/2001; the other half contact-exposed to inoculated animals. Virus excretion, clinical signs and antibody response were measured and virus transmission was quantified. Infected calves showed mild clinical signs which did not affect general health or appetite, and not all contact calves became infected. Dairy cows, on the other hand, showed severe FMD lesions resulting in clinical mastitis, severe lameness and decreased feed intake. Also fever was observed for three consecutive days. All contact cows became infected and showed the same severity of clinical signs. The total and mean daily virus excretion differed significantly between cows and calves (P <0.05). Possibly, virus replication and clinical manifestation are associated, but the underlying mechanism of these differences needs to be elucidated. We did not observe a significant difference in virus transmission between calves and cows

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