Detection of proper insemination time by multiple pregnancy marker pattern (mpmp) recognition  

M.F.W. te Pas (Inventor), H. Woelders (Inventor), A.C. Bouwman (Inventor), B. Hulsegge (Inventor)

Research output: PatentOther research output

Abstract

The invention relates to methods for pregnancy and non-pregnancy testing and also relates to methods allowing determination of proper insemination time to establish pregnancy. The invention provides method to determine whether an inseminated female mammal is pregnant prior to a point in time at which said mammal would be expected to ovulate if non- pregnant, said method comprising taking a biological sample from said mammal prior to said point in time and testing said sample for the presence of a multiple pregnancy marker pattern (MPMP). It is preferred that said sample is tested for the relative expression of progesterone and of at least one marker selected from a group of marker proteins that each contribute to a significantly differential marker expression pattern related to the status pregnancy and is tested to determine whether said mammal is non-pregnant and may be re- inseminated.
Original languageEnglish
Patent numberWO2017158154
Priority date18/03/16
Publication statusPublished - 21 Sep 2017

Fingerprint

Multiple Pregnancy
Insemination
Mammals
Time-to-Pregnancy
Pregnancy
Progesterone
Proteins

Cite this

@misc{f1f6dc4036fe433c8eb0006831bf0d73,
title = "Detection of proper insemination time by multiple pregnancy marker pattern (mpmp) recognition  ",
abstract = "The invention relates to methods for pregnancy and non-pregnancy testing and also relates to methods allowing determination of proper insemination time to establish pregnancy. The invention provides method to determine whether an inseminated female mammal is pregnant prior to a point in time at which said mammal would be expected to ovulate if non- pregnant, said method comprising taking a biological sample from said mammal prior to said point in time and testing said sample for the presence of a multiple pregnancy marker pattern (MPMP). It is preferred that said sample is tested for the relative expression of progesterone and of at least one marker selected from a group of marker proteins that each contribute to a significantly differential marker expression pattern related to the status pregnancy and is tested to determine whether said mammal is non-pregnant and may be re- inseminated.",
author = "{te Pas}, M.F.W. and H. Woelders and A.C. Bouwman and B. Hulsegge",
year = "2017",
month = "9",
day = "21",
language = "English",
type = "Patent",
note = "WO2017158154",

}

TY - PAT

T1 - Detection of proper insemination time by multiple pregnancy marker pattern (mpmp) recognition  

AU - te Pas, M.F.W.

AU - Woelders, H.

AU - Bouwman, A.C.

AU - Hulsegge, B.

PY - 2017/9/21

Y1 - 2017/9/21

N2 - The invention relates to methods for pregnancy and non-pregnancy testing and also relates to methods allowing determination of proper insemination time to establish pregnancy. The invention provides method to determine whether an inseminated female mammal is pregnant prior to a point in time at which said mammal would be expected to ovulate if non- pregnant, said method comprising taking a biological sample from said mammal prior to said point in time and testing said sample for the presence of a multiple pregnancy marker pattern (MPMP). It is preferred that said sample is tested for the relative expression of progesterone and of at least one marker selected from a group of marker proteins that each contribute to a significantly differential marker expression pattern related to the status pregnancy and is tested to determine whether said mammal is non-pregnant and may be re- inseminated.

AB - The invention relates to methods for pregnancy and non-pregnancy testing and also relates to methods allowing determination of proper insemination time to establish pregnancy. The invention provides method to determine whether an inseminated female mammal is pregnant prior to a point in time at which said mammal would be expected to ovulate if non- pregnant, said method comprising taking a biological sample from said mammal prior to said point in time and testing said sample for the presence of a multiple pregnancy marker pattern (MPMP). It is preferred that said sample is tested for the relative expression of progesterone and of at least one marker selected from a group of marker proteins that each contribute to a significantly differential marker expression pattern related to the status pregnancy and is tested to determine whether said mammal is non-pregnant and may be re- inseminated.

M3 - Patent

M1 - WO2017158154

ER -