Detection of pathogenic Streptococcus suis bacteria using magnetic glycoparticles

N.P. Pera, A. Kouki, S. Haataja, H.M. Branderhorst, R.M.J. Liskamp, G.M. Visser, J. Finne, R.J. Pieters

Research output: Contribution to journalArticleAcademicpeer-review

43 Citations (Scopus)

Abstract

Detection of the zoonotic bacterial pathogen Streptococcus suis was achieved using magnetic glycoparticles. The bacteria contain an adhesion protein for the carbohydrate sequence Gal alpha 1,4Gal. After incubation with various amounts of the pathogen, magnetic concentration and ATP detection, bacterial levels down to 10(5) cfu could be detected. Submicrometer particles were needed, since with the larger microparticles the method did not succeed.
Original languageEnglish
Pages (from-to)2425-2429
JournalOrganic & Biomolecular Chemistry
Volume8
Issue number10
DOIs
Publication statusPublished - 2010

Keywords

  • escherichia-coli
  • adhesion
  • recognition
  • nanoparticles
  • inhibition

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