Detection of novel strains of cyprinid herpesvirus closely related to koi herpesvirus

M.Y. Engelsma; K. Way; M.J. Dodge; H.A. Voorbergen-Laarman; V.M. Panzarin; M. Abbadi; M. El-Matbouli; H.F. Skall; S. Kahns; D.M. Stone

doi:10.3354/dao02666

Detection of novel strains of cyprinid herpesvirus closely related to koi herpesvirus

M.Y. Engelsma, K. Way, M.J. Dodge, H.A. Voorbergen-Laarman, V.M. Panzarin, M. Abbadi, M. El-Matbouli, H.F. Skall, S. Kahns, D.M. Stone

Epidemiology, Bio-informatics & Animal models

Research output: Contribution to journal › Article › Academic › peer-review

37 Citations (Scopus)

Abstract

Cyprinid herpesvirus 3 (CyHV-3) or koi herpesvirus (KHV) is a devastating virus of carp. Using generic primers for the DNA polymerase and the major capsid protein genes of cyprinid herpesviruses, nucleotide sequences divergent from previously described CyHV-3 were obtained. At least 3 novel groups of putative CyHV-3-like viruses were identified, sharing 95 to 98% nucleotide identity with CyHV-3 strains. Carp carrying the CyHV-3 variants did not show clinical signs consistent with CyHV-3 infection and originated from locations with no actual CyHV-3 outbreaks. These strains might represent low- or non-pathogenic variants of CyHV-3.

Original language	English
Pages (from-to)	113-120
Journal	Diseases of Aquatic Organisms
Volume	107
Issue number	2
DOIs	https://doi.org/10.3354/dao02666
Publication status	Published - 2013

Keywords

common carp
thymidine kinase
1st detection
genome
aquaculture
cloning
disease
khv

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10.3354/dao02666

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title = "Detection of novel strains of cyprinid herpesvirus closely related to koi herpesvirus",

abstract = "Cyprinid herpesvirus 3 (CyHV-3) or koi herpesvirus (KHV) is a devastating virus of carp. Using generic primers for the DNA polymerase and the major capsid protein genes of cyprinid herpesviruses, nucleotide sequences divergent from previously described CyHV-3 were obtained. At least 3 novel groups of putative CyHV-3-like viruses were identified, sharing 95 to 98% nucleotide identity with CyHV-3 strains. Carp carrying the CyHV-3 variants did not show clinical signs consistent with CyHV-3 infection and originated from locations with no actual CyHV-3 outbreaks. These strains might represent low- or non-pathogenic variants of CyHV-3.",

keywords = "common carp, thymidine kinase, 1st detection, genome, aquaculture, cloning, disease, khv",

author = "M.Y. Engelsma and K. Way and M.J. Dodge and H.A. Voorbergen-Laarman and V.M. Panzarin and M. Abbadi and M. El-Matbouli and H.F. Skall and S. Kahns and D.M. Stone",

year = "2013",

doi = "10.3354/dao02666",

language = "English",

volume = "107",

pages = "113--120",

journal = "Diseases of Aquatic Organisms",

issn = "0177-5103",

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number = "2",

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TY - JOUR

T1 - Detection of novel strains of cyprinid herpesvirus closely related to koi herpesvirus

AU - Engelsma, M.Y.

AU - Way, K.

AU - Dodge, M.J.

AU - Voorbergen-Laarman, H.A.

AU - Panzarin, V.M.

AU - Abbadi, M.

AU - El-Matbouli, M.

AU - Skall, H.F.

AU - Kahns, S.

AU - Stone, D.M.

PY - 2013

Y1 - 2013

N2 - Cyprinid herpesvirus 3 (CyHV-3) or koi herpesvirus (KHV) is a devastating virus of carp. Using generic primers for the DNA polymerase and the major capsid protein genes of cyprinid herpesviruses, nucleotide sequences divergent from previously described CyHV-3 were obtained. At least 3 novel groups of putative CyHV-3-like viruses were identified, sharing 95 to 98% nucleotide identity with CyHV-3 strains. Carp carrying the CyHV-3 variants did not show clinical signs consistent with CyHV-3 infection and originated from locations with no actual CyHV-3 outbreaks. These strains might represent low- or non-pathogenic variants of CyHV-3.

AB - Cyprinid herpesvirus 3 (CyHV-3) or koi herpesvirus (KHV) is a devastating virus of carp. Using generic primers for the DNA polymerase and the major capsid protein genes of cyprinid herpesviruses, nucleotide sequences divergent from previously described CyHV-3 were obtained. At least 3 novel groups of putative CyHV-3-like viruses were identified, sharing 95 to 98% nucleotide identity with CyHV-3 strains. Carp carrying the CyHV-3 variants did not show clinical signs consistent with CyHV-3 infection and originated from locations with no actual CyHV-3 outbreaks. These strains might represent low- or non-pathogenic variants of CyHV-3.

KW - common carp

KW - thymidine kinase

KW - 1st detection

KW - genome

KW - aquaculture

KW - cloning

KW - disease

KW - khv

U2 - 10.3354/dao02666

DO - 10.3354/dao02666

M3 - Article

SN - 0177-5103

VL - 107

SP - 113

EP - 120

JO - Diseases of Aquatic Organisms

JF - Diseases of Aquatic Organisms

IS - 2

ER -

Detection of novel strains of cyprinid herpesvirus closely related to koi herpesvirus

Abstract

Keywords

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