Abstract
The objective of the research described in this thesis was to design amicrofluidicsplatform for the screening ofbiolibraries. Thismicrofluidicplatform can be considered as a technology demonstrator for the screening and sorting of particles smaller than cells like fluorescent-labelled (submicrometer-sized) beads, bacteria and viruses. The particles can even have a relatively low fluorescence yield that can be compensated by longer interrogation times as compared to the ones used in conventional flowcytometrythat is now capable of screening many thousands of cells per minute.
Original language | English |
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Qualification | Doctor of Philosophy |
Awarding Institution |
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Supervisors/Advisors |
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Award date | 28 Nov 2006 |
Place of Publication | [S.l.] |
Print ISBNs | 9789085045632 |
Publication status | Published - 2006 |
Keywords
- bacteriophages
- fluorescent tracers
- fluorescence emission spectroscopy