Detection and sorting of micro-beads and bacteriophages in a microfluidic biochip

B.H. Kunst

Research output: Thesisinternal PhD, WU

Abstract

The objective of the research described in this thesis was to design amicrofluidicsplatform for the screening ofbiolibraries. Thismicrofluidicplatform can be considered as a technology demonstrator for the screening and sorting of particles smaller than cells like fluorescent-labelled (submicrometer-sized) beads, bacteria and viruses. The particles can even have a relatively low fluorescence yield that can be compensated by longer interrogation times as compared to the ones used in conventional flowcytometrythat is now capable of screening many thousands of cells per minute.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Wageningen University
Supervisors/Advisors
  • Visser, Ton, Promotor
  • de Vries, Sacco, Promotor
  • Schots, Arjen, Co-promotor
Award date28 Nov 2006
Place of Publication[S.l.]
Print ISBNs9789085045632
Publication statusPublished - 2006

Keywords

  • bacteriophages
  • fluorescent tracers
  • fluorescence emission spectroscopy

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