Dengue Non-coding RNA: TRIMmed for Transmission

G.P. Göertz; G.P. Pijlman

doi:10.1016/j.chom.2015.07.009

Dengue Non-coding RNA: TRIMmed for Transmission

G.P. Göertz, G.P. Pijlman^*

^*Corresponding author for this work

Research output: Contribution to journal › Editorial › Academic › peer-review

17 Citations (Scopus)

Abstract

Dengue virus RNA is trimmed by the 5'¿3' exoribonuclease XRN1 to produce an abundant, non-coding subgenomic flavivirus RNA (sfRNA) in infected cells. In a recent paper in Science, Manokaran et al. (2015) report that sfRNA binds TRIM25 to evade innate immune sensing of viral RNA by RIG-I.

Original language	English
Pages (from-to)	133-134
Journal	Cell Host & Microbe
Volume	18
Issue number	2
DOIs	https://doi.org/10.1016/j.chom.2015.07.009
Publication status	Published - 2015

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10.1016/j.chom.2015.07.009Licence: Publisher

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title = "Dengue Non-coding RNA: TRIMmed for Transmission",

abstract = "Dengue virus RNA is trimmed by the 5'¿3' exoribonuclease XRN1 to produce an abundant, non-coding subgenomic flavivirus RNA (sfRNA) in infected cells. In a recent paper in Science, Manokaran et al. (2015) report that sfRNA binds TRIM25 to evade innate immune sensing of viral RNA by RIG-I.",

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AB - Dengue virus RNA is trimmed by the 5'¿3' exoribonuclease XRN1 to produce an abundant, non-coding subgenomic flavivirus RNA (sfRNA) in infected cells. In a recent paper in Science, Manokaran et al. (2015) report that sfRNA binds TRIM25 to evade innate immune sensing of viral RNA by RIG-I.

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DO - 10.1016/j.chom.2015.07.009

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JO - Cell Host & Microbe

JF - Cell Host & Microbe

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Dengue Non-coding RNA: TRIMmed for Transmission

Abstract

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