Dengue Non-coding RNA: TRIMmed for Transmission

G.P. Göertz, G.P. Pijlman

Research output: Contribution to journalEditorialAcademicpeer-review

7 Citations (Scopus)


Dengue virus RNA is trimmed by the 5'¿3' exoribonuclease XRN1 to produce an abundant, non-coding subgenomic flavivirus RNA (sfRNA) in infected cells. In a recent paper in Science, Manokaran et al. (2015) report that sfRNA binds TRIM25 to evade innate immune sensing of viral RNA by RIG-I.
Original languageEnglish
Pages (from-to)133-134
JournalCell Host & Microbe
Issue number2
Publication statusPublished - 2015

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