Delivery of genome editing tools by bacterial extracellular vesicles

Yue Liu, Eddy J. Smid, Tjakko Abee, Richard A. Notebaart*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Abstract

Here we propose to use bacterial cells as factories that generate EVs harboring both the RNP complex (or any other CRISPR‐mediated tool) and a specific ligand molecule. The ligand would allow specific binding of EVs to cells with the matching receptors, adding a level of specificity to the delivery, hence stimulating precise genome editing.
Original languageEnglish
Pages (from-to)71-73
Number of pages3
JournalMicrobial Biotechnology
Volume12
Issue number1
DOIs
Publication statusPublished - 1 Jan 2019

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