Deletion of the sigB gene in Bacillus cereus ATCC 14579 leads to hydrogen peroxide hyperresistance

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Abstract

The sigB gene of Bacillus cereus ATCC 14579 encodes the alternative sigma factor B. Deletion of sigB in B. cereus leads to hyperresistance to hydrogen peroxide. The expression of katA, which encodes one of the catalases of B. cereus, is upregulated in the sigB deletion mutant, and this may contribute to the hydrogen peroxide-resistant phenotype
Original languageEnglish
Pages (from-to)6427-6430
JournalApplied and Environmental Microbiology
Volume71
Issue number10
DOIs
Publication statusPublished - 2005

Keywords

  • oxidative stress resistance
  • staphylococcus-aureus
  • sigma(b)
  • identification
  • heat
  • sporulation
  • expression
  • virulence
  • proteins
  • strain

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