Deciphering the RhizosphereMicrobiome for Disease-Suppressive Bacteria

R. Mendes, M. Kruijt, I. de Bruijn, E. Dekkers, M. van der Voort, J.H.M. Schneider, Y.M. Piceno, T.Z. DeSantis, G.L. Andersen, P.A.H.M. Bakker, J.M. Raaijmakers

Research output: Contribution to journalArticleAcademicpeer-review

1085 Citations (Scopus)

Abstract

Disease-suppressive soils are exceptional ecosystems in which crop plants suffer less from specific soil-borne pathogens than expected owing to the activities of other soil microorganisms. For most disease-suppressive soils, the microbes and mechanisms involved in pathogen control are unknown. By coupling PhyloChip-based metagenomics of the rhizosphere microbiome with culture-dependent functional analyses, we identified key bacterial taxa and genes involved in suppression of a fungal root pathogen. More than 33,000 bacterial and archaeal species were detected, with Proteobacteria, Firmicutes, and Actinobacteria consistently associated with disease suppression. Members of the ¿-Proteobacteria were shown to have disease-suppressive activity governed by nonribosomal peptide synthetases. Our data indicate that upon attack by a fungal root pathogen, plants can exploit microbial consortia from soil for protection against infections.
Original languageEnglish
Pages (from-to)1097-1100
JournalScience
Volume332
Issue number6033
DOIs
Publication statusPublished - 2011

Keywords

  • pathogens

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