Death proteases come alive

    Research output: Contribution to journalArticleAcademicpeer-review

    91 Citations (Scopus)

    Abstract

    Cell death in plants exhibits morphological features comparable to caspase-mediated apoptosis in animals, suggesting that plant cell death is executed by (caspase-like) proteases. However, to date, no caspase homologues have been identified in plants and therefore the existence and nature of these plant caspase-like proteases is the subject of much debate. The recent characterization of cell death-associated plant proteases with aspartate-specific cleavage activity demonstrates the involvement in plant programmed cell death of proteolytic activities functionally resembling animal caspases. These findings might explain the observed similarity in cell death morphology between animal and plant cells.
    Original languageEnglish
    Pages (from-to)469-472
    JournalTrends in Plant Science
    Volume9
    Issue number10.
    DOIs
    Publication statusPublished - 2004

    Keywords

    • programmed cell-death
    • caspase-like activity
    • apoptosis
    • gene
    • p35
    • involvement
    • expression
    • inhibitors
    • resistance
    • disease

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