Dataset of liver proteins changed in eu- and hypothyroid female rats upon in vivo exposure to hexabromocyclododecane (HBCD)

I. Miller; T. Serchi; S. Cambier; C. Diepenbroek; J. Renaut; J.H.J. van den Berg; C. Kwadijk; A.C. Gutleb; E. Rijntjes; A.J. Murk

doi:10.1016/j.dib.2016.02.047

Dataset of liver proteins changed in eu- and hypothyroid female rats upon in vivo exposure to hexabromocyclododecane (HBCD)

I. Miller^*, T. Serchi, S. Cambier, C. Diepenbroek, J. Renaut, J.H.J. van den Berg, C. Kwadijk, A.C. Gutleb, E. Rijntjes, A.J. Murk

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

1 Citation (Scopus)

Abstract

Female Wistar rats with different thyroid status (eu-, hypothyroid) were exposed to 0, 3 or 30 mg/kg body weight of the flame retardant HBCD for 7 days. Changes in protein patterns obtained by 2D-DIGE were evaluated, and different animal groups compared taking into account their exposure and thyroid status. Proteins significantly altered in abundance in any of these comparisons were identified by mass spectrometry. These data, together with hormone data of the animals, are discussed in "Hexa-bromocyclododecane (HBCD) induced changes in the liver proteome of eu- and hypothyroid female rats" (Miller et al., 2016) [1].

Original language	English
Article number	7
Pages (from-to)	386-392
Journal	Data in Brief
DOIs	https://doi.org/10.1016/j.dib.2016.02.047
Publication status	Published - 2016

Keywords

HBCD
Hypothyroidism
Lipid metabolism
Liver
Proteomics
Rat

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10.1016/j.dib.2016.02.047Licence: CC BY

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title = "Dataset of liver proteins changed in eu- and hypothyroid female rats upon in vivo exposure to hexabromocyclododecane (HBCD)",

abstract = "Female Wistar rats with different thyroid status (eu-, hypothyroid) were exposed to 0, 3 or 30 mg/kg body weight of the flame retardant HBCD for 7 days. Changes in protein patterns obtained by 2D-DIGE were evaluated, and different animal groups compared taking into account their exposure and thyroid status. Proteins significantly altered in abundance in any of these comparisons were identified by mass spectrometry. These data, together with hormone data of the animals, are discussed in {"}Hexa-bromocyclododecane (HBCD) induced changes in the liver proteome of eu- and hypothyroid female rats{"} (Miller et al., 2016) [1].",

keywords = "HBCD, Hypothyroidism, Lipid metabolism, Liver, Proteomics, Rat",

author = "I. Miller and T. Serchi and S. Cambier and C. Diepenbroek and J. Renaut and {van den Berg}, J.H.J. and C. Kwadijk and A.C. Gutleb and E. Rijntjes and A.J. Murk",

year = "2016",

doi = "10.1016/j.dib.2016.02.047",

language = "English",

pages = "386--392",

journal = "Data in Brief",

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TY - JOUR

T1 - Dataset of liver proteins changed in eu- and hypothyroid female rats upon in vivo exposure to hexabromocyclododecane (HBCD)

AU - Miller, I.

AU - Serchi, T.

AU - Cambier, S.

AU - Diepenbroek, C.

AU - Renaut, J.

AU - van den Berg, J.H.J.

AU - Kwadijk, C.

AU - Gutleb, A.C.

AU - Rijntjes, E.

AU - Murk, A.J.

PY - 2016

Y1 - 2016

N2 - Female Wistar rats with different thyroid status (eu-, hypothyroid) were exposed to 0, 3 or 30 mg/kg body weight of the flame retardant HBCD for 7 days. Changes in protein patterns obtained by 2D-DIGE were evaluated, and different animal groups compared taking into account their exposure and thyroid status. Proteins significantly altered in abundance in any of these comparisons were identified by mass spectrometry. These data, together with hormone data of the animals, are discussed in "Hexa-bromocyclododecane (HBCD) induced changes in the liver proteome of eu- and hypothyroid female rats" (Miller et al., 2016) [1].

AB - Female Wistar rats with different thyroid status (eu-, hypothyroid) were exposed to 0, 3 or 30 mg/kg body weight of the flame retardant HBCD for 7 days. Changes in protein patterns obtained by 2D-DIGE were evaluated, and different animal groups compared taking into account their exposure and thyroid status. Proteins significantly altered in abundance in any of these comparisons were identified by mass spectrometry. These data, together with hormone data of the animals, are discussed in "Hexa-bromocyclododecane (HBCD) induced changes in the liver proteome of eu- and hypothyroid female rats" (Miller et al., 2016) [1].

KW - HBCD

KW - Hypothyroidism

KW - Lipid metabolism

KW - Liver

KW - Proteomics

KW - Rat

U2 - 10.1016/j.dib.2016.02.047

DO - 10.1016/j.dib.2016.02.047

M3 - Article

AN - SCOPUS:84959420180

SP - 386

EP - 392

JO - Data in Brief

JF - Data in Brief

SN - 2352-3409

M1 - 7

ER -

Dataset of liver proteins changed in eu- and hypothyroid female rats upon in vivo exposure to hexabromocyclododecane (HBCD)

Abstract

Keywords

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