Current methods of analysis for the determination of trichothecene mycotoxins in food

J.P. Meneely, F. Ricci, H.P. van Egmond, C.T. Elliott

    Research output: Contribution to journalArticleAcademicpeer-review

    92 Citations (Scopus)

    Abstract

    This article describes the trends in analytical techniques for the determination of trichothecene mycotoxins, namely deoxynivalenol, and T-2 and HT-2 toxins in cereals and cereal products with particular emphasis on screening and rapid approaches. The driving force behind the changing methodologies is mainly attributed to legislative demands. However, for commercial and governmental testing laboratories, the need to use validated official methods is ever increasing to ensure quality assurance of results. Much research has been undertaken to improve screening assays, highlighted by the number of new methods using a variety of formats and platforms, including optical and electrochemical biosensors. Significant advances in the traditional reference methods have also been demonstrated in addition to the emergence of a variety of commercial immunoaffinity and solid-phase extraction columns for clean up. The use of liquid chromatography coupled to tandem mass spectrometry for mycotoxin detection is ever increasing, allowing simultaneous determination of many toxins in various sample matrices.
    Original languageEnglish
    Pages (from-to)192-203
    JournalTrAC : Trends in Analytical Chemistry
    Volume30
    Issue number2
    DOIs
    Publication statusPublished - 2011

    Keywords

    • performance liquid-chromatography
    • differential-pulse polarography
    • tandem mass-spectrometry
    • monoclonal-antibodies
    • electrochemical immunosensor
    • deoxynivalenol don
    • b trichothecenes
    • aflatoxin b-1
    • wheat
    • immunoassay

    Fingerprint Dive into the research topics of 'Current methods of analysis for the determination of trichothecene mycotoxins in food'. Together they form a unique fingerprint.

  • Projects

    Cite this