Cumulative Exposure Assessment of Triazole Pesticides

J.D. van Klaveren, G. van Donkersgoed, H. van der Voet, C. Stephenson, P.E. Boon

    Research output: Book/ReportReportProfessional


    In the EFSA opinion on identification of new approaches to assess cumulative and synergistic risks from pesticides to human health a tiered approach for cumulative risk assessment has been proposed. The first tier is a deterministic approach using average and large portion consumption statistics. The higher tiers include probabilistic exposure assessment and Benchmark Dose (BMD) modeling. The aim of this study is to demonstrate the feasibility and applicability of a higher tier assessment of cumulative exposure using probabilistic modeling in combination with the relative potency factor (RPF) approach. The RPFs are used to weigh the toxicity of each pesticide relative to the toxicity of a chosen index compound (pesticide). In this report the authors address both the short-term and long-term cumulative exposure to triazoles using different statistical models
    Original languageEnglish
    Place of PublicationWageningen
    Number of pages109
    Publication statusPublished - 2009

    Publication series

    NameReport / RIKILT


    • triazoles
    • pesticides
    • food safety
    • probabilistic models

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  • Cite this

    van Klaveren, J. D., van Donkersgoed, G., van der Voet, H., Stephenson, C., & Boon, P. E. (2009). Cumulative Exposure Assessment of Triazole Pesticides. (Report / RIKILT; No. 2009.008). RIKILT.