Culture of Crypthecadinium cohnii for the synthesis of a polyunsaturated fatty acid

C. Ratledge (Inventor), A.J. Anderson (Inventor), K. Kanagachandran (Inventor), D.J. Grantham (Inventor), J.C. Stephenson (Inventor), M.E. Swaaf (Inventor), L. Sijtsma (Inventor)

    Research output: PatentProfessional

    Abstract

    C. cohnii is cultured in a suitable growth medium with acetic acid/acetate as the main carbon source. The acetate is provided, and replenished, by adding acetic acid to the growth medium in response to an increase in pH resulting from the utilisation of acetic acid/acetate by the C. cohnii. The C. cohnii produces relatively high levels of docosahexaenoic acid (DHA). A stationary phase is not essential for satisfactory DHA production.
    Original languageEnglish
    Patent numberWO0104338
    Priority date14/07/99
    Publication statusPublished - 18 Jan 2001

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