Crystal stuctures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate, 2,4-dihydroxybenzoate and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring.

H.A. Schreuder, A. Mattevi, G. Oblomova, K.H. Kalk, W.G.J. Hol, F.J.T. van der Bolt, W.J.H. van Berkel

Research output: Contribution to journalArticleAcademicpeer-review

112 Citations (Scopus)
Original languageEnglish
Pages (from-to)10161-10170
JournalBiochemistry
Volume33
Publication statusPublished - 1994

Cite this