Cronobacter spp., foodborne pathogens threatening neonates and infants

Qiming Chen, Yang Zhu, Zhen Qin, Yongjun Qiu, Liming Zhao*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)


Cronobacter spp. (formerly Enterobacter sakazakii) are special foodborne pathogens. Cronobacter infection can cause necrotizing enterocolitis, sepsis and meningitis in all age groups, especially neonates and infants, with a high fatality of up to 80%, although the infection is rare. Outbreaks of Cronobacter infection are epidemiologically proven to be associated with contaminated powdered infant formula (PIF). Cronobacter spp. can resist dry environments and survive for a long period in food with low water activity. Therefore, Cronobacter spp. have become serious pathogens of neonates and infants, as well as in the dairy industry. In this review, we present the taxonomy, pathogenesis, resistance, detection and control of Cronobacter spp.

Original languageEnglish
Pages (from-to)330-339
JournalFrontiers of Agricultural Science and Engineering
Issue number3
Publication statusPublished - 1 Jul 2018


  • Cronobacter spp.
  • Desiccation resistance
  • Pathogen control
  • Pathogen detection
  • Powdered infant formula


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